Cargando…
G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells
G0/G1 switch gene 2 (G0S2) is known to inhibit lipolysis by inhibiting adipose triglyceride lipase (ATGL). In this report, we dissect the role of G0S2 in ER+ versus ER- breast cancer. Overexpression of G0S2 in ER- cells increased cell proliferation, while G0S2 overexpression in ER+ cells decreased c...
Autores principales: | Corbet, Andrea K., Bikorimana, Emmanuel, Boyd, Raya I., Shokry, Doha, Kries, Kelly, Gupta, Ayush, Paton, Anneliese, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J., Nelson, Erik R., Spinella, Michael J., Singh, Ratnakar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214302/ https://www.ncbi.nlm.nih.gov/pubmed/37086619 http://dx.doi.org/10.1016/j.tranon.2023.101676 |
Ejemplares similares
-
Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy
por: Singh, Ratnakar, et al.
Publicado: (2021) -
Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors
por: Singh, Ratnakar, et al.
Publicado: (2019) -
Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors
por: Singh, Ratnakar, et al.
Publicado: (2019) -
Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors
por: Singh, Ratnakar, et al.
Publicado: (2021) -
HAS2-Ezrin-ER axis plays a role in acquired antiestrogen resistance of ER-positive breast cancer
por: Sun, Xiaodan, et al.
Publicado: (2022)