Genetic variations that influence paclitaxel pharmacokinetics and intracellular effects that may contribute to chemotherapy-induced neuropathy: A narrative review

Taxanes, particularly paclitaxel and docetaxel, are chemotherapeutic agents commonly used to treat breast cancers. A frequent side effect is chemotherapy-induced peripheral neuropathy (CIPN) that occurs in up to 70% of all treated patients and impacts the quality of life during and after treatment....

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Detalles Bibliográficos
Autores principales: Johnson, Ken B., Sharma, Anukriti, Henry, N. Lynn, Wei, Mei, Bie, Bihua, Hershberger, Courtney E., Rhoades, Emily E., Sen, Alper, Johnson, Ryan E., Steenblik, Jacob, Hockings, Jennifer, Budd, G. Thomas, Eng, Charis, Foss, Joseph, Rotroff, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214418/
https://www.ncbi.nlm.nih.gov/pubmed/37251592
http://dx.doi.org/10.3389/fpain.2023.1139883

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