Cargando…

Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692

[Image: see text] The domain of unknown function 692 (DUF692) is an emerging family of post-translational modification enzymes involved in the biosynthesis of ribosomally synthesized and post-translationally modified peptide (RiPP) natural products. Members of this family are multinuclear iron-conta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ayikpoe, Richard S., Zhu, Lingyang, Chen, Jeff Y., Ting, Chi P., van der Donk, Wilfred A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214503/ https://www.ncbi.nlm.nih.gov/pubmed/37252350 http://dx.doi.org/10.1021/acscentsci.3c00160

Ejemplares similares

A remarkable transformation catalyzed by a domain-of-unknown-function 692 during the biosynthesis of a new RiPP natural product
por: Ayikpoe, Richard S., et al.
Publicado: (2023)

Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
por: Miller, Fredarla S., et al.
Publicado: (2021)

Redirecting RiPP Biosynthetic Enzymes to Proteins and Backbone-Modified Substrates
por: Walker, Joshua A., et al.
Publicado: (2022)

Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products
por: Burkhart, Brandon J., et al.
Publicado: (2017)

Radical SAM Enzymes in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs)
por: Benjdia, Alhosna, et al.
Publicado: (2017)

NeuRiPP: Neural network identification of RiPP precursor peptides
por: de los Santos, Emmanuel L. C.
Publicado: (2019)

Global Genome Mining Reveals the Distribution of Diverse Thioamidated RiPP Biosynthesis Gene Clusters
por: Malit, Jessie James Limlingan, et al.
Publicado: (2021)

Assessing the Combinatorial Potential of the RiPP Cyanobactin tru Pathway
por: Ruffner, Duane E., et al.
Publicado: (2014)

Cytochromes P450 involved in bacterial RiPP biosyntheses
por: Kunakom, Sylvia, et al.
Publicado: (2023)

Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor
por: Dong, Shi-Hui, et al.
Publicado: (2018)

Recent Advances in the Discovery and Biosynthetic Study of Eukaryotic RiPP Natural Products
por: Luo, Shangwen, et al.
Publicado: (2019)

Biosynthesis and Heterologous Expression of Cacaoidin, the First Member of the Lanthidin Family of RiPPs
por: Román-Hurtado, Fernando, et al.
Publicado: (2021)

RaS-RiPPs in Streptococci and the Human Microbiome
por: Clark, Kenzie A., et al.
Publicado: (2022)

RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery
por: Kloosterman, Alexander M., et al.
Publicado: (2020)

Genome-Guided Discovery of the First Myxobacterial Biarylitide Myxarylin Reveals Distinct C–N Biaryl Crosslinking in RiPP Biosynthesis
por: Hug, Joachim J., et al.
Publicado: (2021)

Translation-Targeting RiPPs and Where to Find Them
por: Travin, Dmitrii Y., et al.
Publicado: (2020)

Exploring fungal RiPPs from the perspective of chemical ecology
por: Ford, R. E., et al.
Publicado: (2022)

Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound
por: Rued, Britta E., et al.
Publicado: (2021)

Engineering lanthipeptides by introducing a large variety of RiPP modifications to obtain new-to-nature bioactive peptides
por: Fu, Yuxin, et al.
Publicado: (2023)

Mechanisms of action of ribosomally synthesized and posttranslationally modified peptides (RiPPs)
por: Cao, Li, et al.
Publicado: (2021)

Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides
por: Kloosterman, Alexander M., et al.
Publicado: (2020)

A Leader-Guided Substrate Tolerant RiPP Brominase Allows Suzuki–Miyaura Cross-Coupling Reactions for Peptides and Proteins
por: Nguyen, Nguyet A., et al.
Publicado: (2023)

RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin α-N-methylated peptide natural product
por: Crone, K. K., et al.
Publicado: (2023)

Bioinformatic mining for RiPP biosynthetic gene clusters in Bacteroidales reveals possible new subfamily architectures and novel natural products
por: Fernandez-Cantos, Maria Victoria, et al.
Publicado: (2023)

RiPPMiner: a bioinformatics resource for deciphering chemical structures of RiPPs based on prediction of cleavage and cross-links
por: Agrawal, Priyesh, et al.
Publicado: (2017)

Antiviral activities and applications of ribosomally synthesized and post-translationally modified peptides (RiPPs)
por: Fu, Yuxin, et al.
Publicado: (2021)

Leveraging Substrate Promiscuity of a Radical S-Adenosyl-L-methionine RiPP Maturase toward Intramolecular Peptide Cross-Linking Applications
por: Eastman, Karsten A. S., et al.
Publicado: (2022)

Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria
por: Letzel, Anne-Catrin, et al.
Publicado: (2014)

BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins
por: van Heel, Auke J, et al.
Publicado: (2018)

Challenges and advances in genome mining of ribosomally synthesized and post-translationally modified peptides (RiPPs)
por: Zhong, Zheng, et al.
Publicado: (2020)

Erratum for Rued et al., “Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound”
por: Rued, Britta E., et al.
Publicado: (2021)

Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways
por: Bobeica, Silvia C., et al.
Publicado: (2020)

Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups
por: Nguyen, Dinh T., et al.
Publicado: (2023)

Novel approach in whole genome mining and transcriptome analysis reveal conserved RiPPs in Trichoderma spp
por: Vignolle, Gabriel A., et al.
Publicado: (2020)

Editorial: Bacteriocins and Other Ribosomally Synthesised and Post-translationally Modified Peptides (RiPPs) as Alternatives to Antibiotics
por: Mathur, Harsh, et al.
Publicado: (2021)

Correction: Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways
por: Bobeica, Silvia C., et al.
Publicado: (2020)

syn-Elimination of glutamylated threonine in lanthipeptide biosynthesis
por: Sarksian, Raymond, et al.
Publicado: (2022)

Selective Modification of Ribosomally Synthesized and Post‐Translationally Modified Peptides (RiPPs) through Diels–Alder Cycloadditions on Dehydroalanine Residues
por: de Vries, Reinder H., et al.
Publicado: (2019)

Overall Retention of Methyl Stereochemistry during B(12)-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis
por: McLaughlin, Martin I., et al.
Publicado: (2021)

Irwin & Rippe's medicina intensiva /
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_fbak9nlj37u9a9p1hfkfu0uvvp