A Systematic Approach to the Discovery of Protein–Protein Interaction Stabilizers

[Image: see text] Dysregulation of protein–protein interactions (PPIs) commonly leads to disease. PPI stabilization has only recently been systematically explored for drug discovery despite being a powerful approach to selectively target intrinsically disordered proteins and hub proteins, like 14-3-...

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Detalles Bibliográficos
Autores principales: Kenanova, Dyana N., Visser, Emira J., Virta, Johanna M., Sijbesma, Eline, Centorrino, Federica, Vickery, Holly R., Zhong, Mengqi, Neitz, R. Jeffrey, Brunsveld, Luc, Ottmann, Christian, Arkin, Michelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214524/
https://www.ncbi.nlm.nih.gov/pubmed/37252362
http://dx.doi.org/10.1021/acscentsci.2c01449

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