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Accelerated Chemical Reaction Optimization Using Multi-Task Learning

[Image: see text] Functionalization of C–H bonds is a key challenge in medicinal chemistry, particularly for fragment-based drug discovery (FBDD) where such transformations require execution in the presence of polar functionality necessary for protein binding. Recent work has shown the effectiveness...

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Detalles Bibliográficos
Autores principales:	Taylor, Connor J., Felton, Kobi C., Wigh, Daniel, Jeraal, Mohammed I., Grainger, Rachel, Chessari, Gianni, Johnson, Christopher N., Lapkin, Alexei A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214532/ https://www.ncbi.nlm.nih.gov/pubmed/37252348 http://dx.doi.org/10.1021/acscentsci.3c00050

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