Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation

BACKGROUND: Idiosyncratic drug-induced liver injury (IDILI) is common in hepatology practices and, in some cases, lethal. Increasing evidence show that tricyclic antidepressants (TCAs) can induce IDILI in clinical applications but the underlying mechanisms are still poorly understood. METHODS: We as...

Descripción completa

Detalles Bibliográficos
Autores principales: Mu, Wenqing, Xu, Guang, Wang, Zhilei, Li, Qiang, Sun, Siqiao, Qin, Qin, Li, Zhiyong, Shi, Wei, Dai, Wenzhang, Zhan, Xiaoyan, Wang, Jiabo, Bai, Zhaofang, Xiao, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214596/
https://www.ncbi.nlm.nih.gov/pubmed/37231437
http://dx.doi.org/10.1186/s12964-023-01128-x

Ejemplares similares

Ejemplares similares