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Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis- and senescence-related genes in swine adipose-derived mesenchymal stem/stromal cells

BACKGROUND: Obesity dysregulates key biological processes underlying the functional homeostasis, fate decisions, and reparative potential of mesenchymal stem/stromal cells (MSCs). Mechanisms directing obesity-induced phenotypic alterations in MSCs remain unclear, but emerging drivers include dynamic...

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Detalles Bibliográficos
Autores principales:	Glasstetter, Logan M., Oderinde, Tomiwa S., Mirchandani, Mohit, Rajagopalan, Kamalnath Sankaran, Barsom, Samer H., Thaler, Roman, Siddiqi, Sarosh, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., van Wijnen, Andre J., Eirin, Alfonso, Lerman, Lilach O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214739/ https://www.ncbi.nlm.nih.gov/pubmed/37231414 http://dx.doi.org/10.1186/s13287-023-03372-x

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