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The “humanized” N‐glycosylation pathway in CRISPR/Cas9‐edited Nicotiana benthamiana significantly enhances the immunogenicity of a S/preS1 Hepatitis B Virus antigen and the virus‐neutralizing antibody response in vaccinated mice

The recent SARS‐CoV‐2 pandemic has taught the world a costly lesson about the devastating consequences of viral disease outbreaks but also, the remarkable impact of vaccination in limiting life and economic losses. Vaccination against human Hepatitis B Virus (HBV), a major human pathogen affecting 2...

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Detalles Bibliográficos
Autores principales: Pantazica, Ana‐Maria, van Eerde, André, Dobrica, Mihaela‐Olivia, Caras, Iuliana, Ionescu, Irina, Costache, Adriana, Tucureanu, Catalin, Steen, Hege, Lazar, Catalin, Heldal, Inger, Haugslien, Sissel, Onu, Adrian, Stavaru, Crina, Branza‐Nichita, Norica, Liu Clarke, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214758/
https://www.ncbi.nlm.nih.gov/pubmed/36779605
http://dx.doi.org/10.1111/pbi.14028