Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds

The Er(OTf)(3)-catalyzed cascade cyclization reaction of para-quinone methides (p-QMs) with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes. Herein, we not only propose a novel cyclization st...

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Detalles Bibliográficos
Autores principales: Bao, Xiaobo, Yu, Wei, Wang, Lilin, Dong, Xu, Wang, Guoli, Chen, Weilin, Li, Fei, Chen, Dongyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214920/
https://www.ncbi.nlm.nih.gov/pubmed/37250229
http://dx.doi.org/10.1039/d3ra02267f
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author Bao, Xiaobo
Yu, Wei
Wang, Lilin
Dong, Xu
Wang, Guoli
Chen, Weilin
Li, Fei
Chen, Dongyin
author_facet Bao, Xiaobo
Yu, Wei
Wang, Lilin
Dong, Xu
Wang, Guoli
Chen, Weilin
Li, Fei
Chen, Dongyin
author_sort Bao, Xiaobo
collection PubMed
description The Er(OTf)(3)-catalyzed cascade cyclization reaction of para-quinone methides (p-QMs) with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes. Herein, we not only propose a novel cyclization strategy of p-QMs, but also provide an easy access to structurally diverse coumarins and chromenes.
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spelling pubmed-102149202023-05-27 Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds Bao, Xiaobo Yu, Wei Wang, Lilin Dong, Xu Wang, Guoli Chen, Weilin Li, Fei Chen, Dongyin RSC Adv Chemistry The Er(OTf)(3)-catalyzed cascade cyclization reaction of para-quinone methides (p-QMs) with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes. Herein, we not only propose a novel cyclization strategy of p-QMs, but also provide an easy access to structurally diverse coumarins and chromenes. The Royal Society of Chemistry 2023-05-26 /pmc/articles/PMC10214920/ /pubmed/37250229 http://dx.doi.org/10.1039/d3ra02267f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Bao, Xiaobo
Yu, Wei
Wang, Lilin
Dong, Xu
Wang, Guoli
Chen, Weilin
Li, Fei
Chen, Dongyin
Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title_full Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title_fullStr Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title_full_unstemmed Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title_short Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
title_sort synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4h-chromenes via er(otf)(3)-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214920/
https://www.ncbi.nlm.nih.gov/pubmed/37250229
http://dx.doi.org/10.1039/d3ra02267f
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