Cargando…

Oral microbiota in children with type 1 diabetes mellitus

INTRODUCTION: The oral cavity is a unique ecosystem in which the microbiome is formed by the colonization of billions of bacteria, viruses, and fungi. AIM OF THE STUDY: was to assess the quality and quantity of bacterial microbiota of the oral cavity in children with type 1 diabetes in comparison to...

Descripción completa

Detalles Bibliográficos
Autores principales: Pachoński, Marek, Koczor-Rozmus, Aleksandra, Mocny-Pachońska, Katarzyna, Łanowy, Patrycja, Mertas, Anna, Jarosz-Chobot, Przemysława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214943/
https://www.ncbi.nlm.nih.gov/pubmed/33878853
http://dx.doi.org/10.5114/pedm.2021.104343
_version_ 1785047946431037440
author Pachoński, Marek
Koczor-Rozmus, Aleksandra
Mocny-Pachońska, Katarzyna
Łanowy, Patrycja
Mertas, Anna
Jarosz-Chobot, Przemysława
author_facet Pachoński, Marek
Koczor-Rozmus, Aleksandra
Mocny-Pachońska, Katarzyna
Łanowy, Patrycja
Mertas, Anna
Jarosz-Chobot, Przemysława
author_sort Pachoński, Marek
collection PubMed
description INTRODUCTION: The oral cavity is a unique ecosystem in which the microbiome is formed by the colonization of billions of bacteria, viruses, and fungi. AIM OF THE STUDY: was to assess the quality and quantity of bacterial microbiota of the oral cavity in children with type 1 diabetes in comparison to healthy children. MATERIAL AND METHODS: The study group consisted of 50 randomly selected type 1 diabetic children aged 10–18 years divided into 2 groups (25 people each) according to the level of diabetes control: well-controlled group (WC) – HbA(1c) ≤ 7.5%) and poorly-controlled group (PC) – HbA(1c) > 7.5%. The control group (GC) consisted of 25 randomly selected children with no systemic diseases. The material for microbiological tests was collected as two swabs: one from the bottom of the oral cavity and the other one from the posterior part of the dorsum of the tongue). RESULTS: The statistical analysis revealed statistically significant differences in the total number of isolated microorganisms between PC and GC (post hoc test p = 0.003) and WC and GC (post hoc test p < 0.001). There were no statistically significant differences in the number of isolated microorganisms between PC and WC (p = 0.195). CONCLUSIONS: Oral microbiome in type 1 diabetic children is significantly quantitatively different in comparison to healthy children. There are also visible qualitative differences in the profile of oral microbiota in type 1 diabetic children and healthy children.
format Online
Article
Text
id pubmed-10214943
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-102149432023-06-05 Oral microbiota in children with type 1 diabetes mellitus Pachoński, Marek Koczor-Rozmus, Aleksandra Mocny-Pachońska, Katarzyna Łanowy, Patrycja Mertas, Anna Jarosz-Chobot, Przemysława Pediatr Endocrinol Diabetes Metab Original paper | Praca oryginalna INTRODUCTION: The oral cavity is a unique ecosystem in which the microbiome is formed by the colonization of billions of bacteria, viruses, and fungi. AIM OF THE STUDY: was to assess the quality and quantity of bacterial microbiota of the oral cavity in children with type 1 diabetes in comparison to healthy children. MATERIAL AND METHODS: The study group consisted of 50 randomly selected type 1 diabetic children aged 10–18 years divided into 2 groups (25 people each) according to the level of diabetes control: well-controlled group (WC) – HbA(1c) ≤ 7.5%) and poorly-controlled group (PC) – HbA(1c) > 7.5%. The control group (GC) consisted of 25 randomly selected children with no systemic diseases. The material for microbiological tests was collected as two swabs: one from the bottom of the oral cavity and the other one from the posterior part of the dorsum of the tongue). RESULTS: The statistical analysis revealed statistically significant differences in the total number of isolated microorganisms between PC and GC (post hoc test p = 0.003) and WC and GC (post hoc test p < 0.001). There were no statistically significant differences in the number of isolated microorganisms between PC and WC (p = 0.195). CONCLUSIONS: Oral microbiome in type 1 diabetic children is significantly quantitatively different in comparison to healthy children. There are also visible qualitative differences in the profile of oral microbiota in type 1 diabetic children and healthy children. Termedia Publishing House 2021-04-20 2021-06 /pmc/articles/PMC10214943/ /pubmed/33878853 http://dx.doi.org/10.5114/pedm.2021.104343 Text en Copyright © Polish Society of Pediatric Endocrinology and Diabetes https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), allowing third parties to download and share its works but not commercially purposes or to create derivative works.
spellingShingle Original paper | Praca oryginalna
Pachoński, Marek
Koczor-Rozmus, Aleksandra
Mocny-Pachońska, Katarzyna
Łanowy, Patrycja
Mertas, Anna
Jarosz-Chobot, Przemysława
Oral microbiota in children with type 1 diabetes mellitus
title Oral microbiota in children with type 1 diabetes mellitus
title_full Oral microbiota in children with type 1 diabetes mellitus
title_fullStr Oral microbiota in children with type 1 diabetes mellitus
title_full_unstemmed Oral microbiota in children with type 1 diabetes mellitus
title_short Oral microbiota in children with type 1 diabetes mellitus
title_sort oral microbiota in children with type 1 diabetes mellitus
topic Original paper | Praca oryginalna
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214943/
https://www.ncbi.nlm.nih.gov/pubmed/33878853
http://dx.doi.org/10.5114/pedm.2021.104343
work_keys_str_mv AT pachonskimarek oralmicrobiotainchildrenwithtype1diabetesmellitus
AT koczorrozmusaleksandra oralmicrobiotainchildrenwithtype1diabetesmellitus
AT mocnypachonskakatarzyna oralmicrobiotainchildrenwithtype1diabetesmellitus
AT łanowypatrycja oralmicrobiotainchildrenwithtype1diabetesmellitus
AT mertasanna oralmicrobiotainchildrenwithtype1diabetesmellitus
AT jaroszchobotprzemysława oralmicrobiotainchildrenwithtype1diabetesmellitus