Interstitial deletion of the Apc locus in β-catenin-overexpressing cells is a signature of radiation-induced intestinal tumors in C3B6F1 Apc(Min)(/+) mice

Recent studies have identified interstitial deletions in the cancer genome as a radiation-related mutational signature, although most of them do not fall on cancer driver genes. Pioneering studies in the field have indicated the presence of loss of heterozygosity (LOH) spanning Apc in a subset of sp...

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Detalles Bibliográficos
Autores principales: Yanagihara, Hiromi, Morioka, Takamitsu, Yamazaki, Shunsuke, Yamada, Yutaka, Tachibana, Hirotaka, Daino, Kazuhiro, Tsuruoka, Chizuru, Amasaki, Yoshiko, Kaminishi, Mutsumi, Imaoka, Tatsuhiko, Kakinuma, Shizuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215001/
https://www.ncbi.nlm.nih.gov/pubmed/37117033
http://dx.doi.org/10.1093/jrr/rrad021

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