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Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis

Nephropathy is the most prevalent microvascular disorder in diabetes mellitus. Oxidative stress and inflammatory cascade provoked by the persistent hyperglycemic milieu play integral roles in the aggravation of renal injury and fibrosis. We explored the impact of biochanin A (BCA), an isoflavonoid,...

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Detalles Bibliográficos
Autores principales: Ram, Chetan, Gairola, Shobhit, Verma, Shobhit, Mugale, Madhav Nilakanth, Bonam, Srinivasa Reddy, Murty, Upadhyayula Suryanarayana, Sahu, Bidya Dhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215298/
https://www.ncbi.nlm.nih.gov/pubmed/37237918
http://dx.doi.org/10.3390/antiox12051052

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