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Diflunisal Attenuates Virulence Factor Gene Regulation and Phenotypes in Staphylococcus aureus

Virulence factor expression is integral to pathogenicity of Staphylococcus aureus. We previously demonstrated that aspirin, through its major metabolite, salicylic acid (SAL), modulates S. aureus virulence phenotypes in vitro and in vivo. We compared salicylate metabolites and a structural analogue...

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Detalles Bibliográficos
Autores principales: Chan, Liana C., Park, Mihyun, Lee, Hong K., Chaili, Siyang, Xiong, Yan Q., Bayer, Arnold S., Proctor, Richard A., Yeaman, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215304/
https://www.ncbi.nlm.nih.gov/pubmed/37237805
http://dx.doi.org/10.3390/antibiotics12050902