Cargando…
Diflunisal Attenuates Virulence Factor Gene Regulation and Phenotypes in Staphylococcus aureus
Virulence factor expression is integral to pathogenicity of Staphylococcus aureus. We previously demonstrated that aspirin, through its major metabolite, salicylic acid (SAL), modulates S. aureus virulence phenotypes in vitro and in vivo. We compared salicylate metabolites and a structural analogue...
Autores principales: | Chan, Liana C., Park, Mihyun, Lee, Hong K., Chaili, Siyang, Xiong, Yan Q., Bayer, Arnold S., Proctor, Richard A., Yeaman, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215304/ https://www.ncbi.nlm.nih.gov/pubmed/37237805 http://dx.doi.org/10.3390/antibiotics12050902 |
Ejemplares similares
-
Diflunisal and Analogue Pharmacophores Mediating Suppression of Virulence Phenotypes in Staphylococcus aureus
por: Chan, Liana C., et al.
Publicado: (2023) -
Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection
por: Li, Liang, et al.
Publicado: (2019) -
Gp05, a Prophage-Encoded Virulence Factor, Contributes to Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection
por: Li, Yi, et al.
Publicado: (2023) -
New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections
por: Li, Liang, et al.
Publicado: (2021) -
Proteomic and Membrane Lipid Correlates of Re-duced Host Defense Peptide Susceptibility in a snoD Mutant of Staphylococcus aureus
por: Kohler, Christian, et al.
Publicado: (2019)