Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein–Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis

Ulcerative colitis (UC) is an idiopathic inflammatory disease of unknown etiology possibly associated with intestinal inflammation and oxidative stress. Molecular hybridization by combining two drug fragments to achieve a common pharmacological goal represents a novel strategy. The Kelch-like ECH-as...

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Detalles Bibliográficos
Autores principales: Zhang, Xian, Cui, Keni, Wang, Xiaolu, Tong, Yuanyuan, Liu, Chihong, Zhu, Yuechao, You, Qidong, Jiang, Zhengyu, Guo, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215391/
https://www.ncbi.nlm.nih.gov/pubmed/37237928
http://dx.doi.org/10.3390/antiox12051062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215391/
https://www.ncbi.nlm.nih.gov/pubmed/37237928
http://dx.doi.org/10.3390/antiox12051062

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