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The Effectiveness of Imipenem–Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase

Background: Ceftazidime-avibactam was approved by the FDA to treat infections caused by Enterobacterales carrying bla(KPC-2). However, variants of KPC-2 with amino acid substitutions at position 179 have emerged and confer resistance to ceftazidime-avibactam. Methods: The activity of imipenem-releba...

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Detalles Bibliográficos
Autores principales:	Papp-Wallace, Krisztina M., Barnes, Melissa D., Taracila, Magdalena A., Bethel, Christopher R., Rutter, Joseph D., Zeiser, Elise T., Young, Katherine, Bonomo, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215400/ https://www.ncbi.nlm.nih.gov/pubmed/37237794 http://dx.doi.org/10.3390/antibiotics12050892

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