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3D Bioprinting for Vascularization

In the world of clinic treatments, 3D-printed tissue constructs have emerged as a less invasive treatment method for various ailments. Printing processes, scaffold and scaffold free materials, cells used, and imaging for analysis are all factors that must be observed in order to develop successful 3...

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Autores principales: Mir, Amatullah, Lee, Eugenia, Shih, Wesley, Koljaka, Sarah, Wang, Anya, Jorgensen, Caitlin, Hurr, Riley, Dave, Amartya, Sudheendra, Krupa, Hibino, Narutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215405/
https://www.ncbi.nlm.nih.gov/pubmed/37237676
http://dx.doi.org/10.3390/bioengineering10050606
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author Mir, Amatullah
Lee, Eugenia
Shih, Wesley
Koljaka, Sarah
Wang, Anya
Jorgensen, Caitlin
Hurr, Riley
Dave, Amartya
Sudheendra, Krupa
Hibino, Narutoshi
author_facet Mir, Amatullah
Lee, Eugenia
Shih, Wesley
Koljaka, Sarah
Wang, Anya
Jorgensen, Caitlin
Hurr, Riley
Dave, Amartya
Sudheendra, Krupa
Hibino, Narutoshi
author_sort Mir, Amatullah
collection PubMed
description In the world of clinic treatments, 3D-printed tissue constructs have emerged as a less invasive treatment method for various ailments. Printing processes, scaffold and scaffold free materials, cells used, and imaging for analysis are all factors that must be observed in order to develop successful 3D tissue constructs for clinical applications. However, current research in 3D bioprinting model development lacks diverse methods of successful vascularization as a result of issues with scaling, size, and variations in printing method. This study analyzes the methods of printing, bioinks used, and analysis techniques in 3D bioprinting for vascularization. These methods are discussed and evaluated to determine the most optimal strategies of 3D bioprinting for successful vascularization. Integrating stem and endothelial cells in prints, selecting the type of bioink according to its physical properties, and choosing a printing method according to physical properties of the desired printed tissue are steps that will aid in the successful development of a bioprinted tissue and its vascularization.
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spelling pubmed-102154052023-05-27 3D Bioprinting for Vascularization Mir, Amatullah Lee, Eugenia Shih, Wesley Koljaka, Sarah Wang, Anya Jorgensen, Caitlin Hurr, Riley Dave, Amartya Sudheendra, Krupa Hibino, Narutoshi Bioengineering (Basel) Review In the world of clinic treatments, 3D-printed tissue constructs have emerged as a less invasive treatment method for various ailments. Printing processes, scaffold and scaffold free materials, cells used, and imaging for analysis are all factors that must be observed in order to develop successful 3D tissue constructs for clinical applications. However, current research in 3D bioprinting model development lacks diverse methods of successful vascularization as a result of issues with scaling, size, and variations in printing method. This study analyzes the methods of printing, bioinks used, and analysis techniques in 3D bioprinting for vascularization. These methods are discussed and evaluated to determine the most optimal strategies of 3D bioprinting for successful vascularization. Integrating stem and endothelial cells in prints, selecting the type of bioink according to its physical properties, and choosing a printing method according to physical properties of the desired printed tissue are steps that will aid in the successful development of a bioprinted tissue and its vascularization. MDPI 2023-05-18 /pmc/articles/PMC10215405/ /pubmed/37237676 http://dx.doi.org/10.3390/bioengineering10050606 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mir, Amatullah
Lee, Eugenia
Shih, Wesley
Koljaka, Sarah
Wang, Anya
Jorgensen, Caitlin
Hurr, Riley
Dave, Amartya
Sudheendra, Krupa
Hibino, Narutoshi
3D Bioprinting for Vascularization
title 3D Bioprinting for Vascularization
title_full 3D Bioprinting for Vascularization
title_fullStr 3D Bioprinting for Vascularization
title_full_unstemmed 3D Bioprinting for Vascularization
title_short 3D Bioprinting for Vascularization
title_sort 3d bioprinting for vascularization
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215405/
https://www.ncbi.nlm.nih.gov/pubmed/37237676
http://dx.doi.org/10.3390/bioengineering10050606
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