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The Antimicrobial Effects of Colistin Encapsulated in Chelating Complex Micelles for the Treatment of Multi-Drug-Resistant Gram-Negative Bacteria: A Pharmacokinetic Study

Background: Infections caused by multi-drug-resistant Gram-negative bacteria (MDR-GNB) are an emerging problem globally. Colistin is the last-sort antibiotic for MDR-GNB, but its toxicity limits its clinical use. We aimed to test the efficacy of colistin-loaded micelles (CCM-CL) against drug-resista...

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Detalles Bibliográficos
Autores principales:	Liao, Wei-Chuan, Wang, Chau-Hui, Sun, Tzu-Hui, Su, Yu-Cheng, Chen, Chia-Hung, Chang, Wen-Teng, Chen, Po-Lin, Shiue, Yow-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215448/ https://www.ncbi.nlm.nih.gov/pubmed/37237739 http://dx.doi.org/10.3390/antibiotics12050836

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