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Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans

Even with over 80% of the population being vaccinated against COVID-19, the disease continues to claim victims. Therefore, it is crucial to have a secure Computer-Aided Diagnostic system that can assist in identifying COVID-19 and determining the necessary level of care. This is especially important...

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Autores principales: Motta, Pedro Crosara, Cortez, Paulo César, Silva, Bruno R. S., Yang, Guang, de Albuquerque, Victor Hugo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215490/
https://www.ncbi.nlm.nih.gov/pubmed/37237599
http://dx.doi.org/10.3390/bioengineering10050529
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author Motta, Pedro Crosara
Cortez, Paulo César
Silva, Bruno R. S.
Yang, Guang
de Albuquerque, Victor Hugo C.
author_facet Motta, Pedro Crosara
Cortez, Paulo César
Silva, Bruno R. S.
Yang, Guang
de Albuquerque, Victor Hugo C.
author_sort Motta, Pedro Crosara
collection PubMed
description Even with over 80% of the population being vaccinated against COVID-19, the disease continues to claim victims. Therefore, it is crucial to have a secure Computer-Aided Diagnostic system that can assist in identifying COVID-19 and determining the necessary level of care. This is especially important in the Intensive Care Unit to monitor disease progression or regression in the fight against this epidemic. To accomplish this, we merged public datasets from the literature to train lung and lesion segmentation models with five different distributions. We then trained eight CNN models for COVID-19 and Common-Acquired Pneumonia classification. If the examination was classified as COVID-19, we quantified the lesions and assessed the severity of the full CT scan. To validate the system, we used Resnetxt101 Unet++ and Mobilenet Unet for lung and lesion segmentation, respectively, achieving accuracy of 98.05%, F1-score of 98.70%, precision of 98.7%, recall of 98.7%, and specificity of 96.05%. This was accomplished in just 19.70 s per full CT scan, with external validation on the SPGC dataset. Finally, when classifying these detected lesions, we used Densenet201 and achieved accuracy of 90.47%, F1-score of 93.85%, precision of 88.42%, recall of 100.0%, and specificity of 65.07%. The results demonstrate that our pipeline can correctly detect and segment lesions due to COVID-19 and Common-Acquired Pneumonia in CT scans. It can differentiate these two classes from normal exams, indicating that our system is efficient and effective in identifying the disease and assessing the severity of the condition.
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spelling pubmed-102154902023-05-27 Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans Motta, Pedro Crosara Cortez, Paulo César Silva, Bruno R. S. Yang, Guang de Albuquerque, Victor Hugo C. Bioengineering (Basel) Article Even with over 80% of the population being vaccinated against COVID-19, the disease continues to claim victims. Therefore, it is crucial to have a secure Computer-Aided Diagnostic system that can assist in identifying COVID-19 and determining the necessary level of care. This is especially important in the Intensive Care Unit to monitor disease progression or regression in the fight against this epidemic. To accomplish this, we merged public datasets from the literature to train lung and lesion segmentation models with five different distributions. We then trained eight CNN models for COVID-19 and Common-Acquired Pneumonia classification. If the examination was classified as COVID-19, we quantified the lesions and assessed the severity of the full CT scan. To validate the system, we used Resnetxt101 Unet++ and Mobilenet Unet for lung and lesion segmentation, respectively, achieving accuracy of 98.05%, F1-score of 98.70%, precision of 98.7%, recall of 98.7%, and specificity of 96.05%. This was accomplished in just 19.70 s per full CT scan, with external validation on the SPGC dataset. Finally, when classifying these detected lesions, we used Densenet201 and achieved accuracy of 90.47%, F1-score of 93.85%, precision of 88.42%, recall of 100.0%, and specificity of 65.07%. The results demonstrate that our pipeline can correctly detect and segment lesions due to COVID-19 and Common-Acquired Pneumonia in CT scans. It can differentiate these two classes from normal exams, indicating that our system is efficient and effective in identifying the disease and assessing the severity of the condition. MDPI 2023-04-26 /pmc/articles/PMC10215490/ /pubmed/37237599 http://dx.doi.org/10.3390/bioengineering10050529 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Motta, Pedro Crosara
Cortez, Paulo César
Silva, Bruno R. S.
Yang, Guang
de Albuquerque, Victor Hugo C.
Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title_full Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title_fullStr Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title_full_unstemmed Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title_short Automatic COVID-19 and Common-Acquired Pneumonia Diagnosis Using Chest CT Scans
title_sort automatic covid-19 and common-acquired pneumonia diagnosis using chest ct scans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215490/
https://www.ncbi.nlm.nih.gov/pubmed/37237599
http://dx.doi.org/10.3390/bioengineering10050529
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