Mitochondrial ROS Accumulation Contributes to Maternal Hypertension and Impaired Remodeling of Spiral Artery but Not IUGR in a Rat PE Model Caused by Maternal Glucocorticoid Exposure

Increased maternal glucocorticoid levels have been implicated as a risk factor for preeclampsia (PE) development. We found that pregnant rats exposed to dexamethasone (DEX) showed hallmarks of PE features, impaired spiral artery (SA) remodeling, and elevated circulatory levels of sFlt1, sEng IL-1β,...

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Detalles Bibliográficos
Autores principales: Long, Jing, Huang, Yan, Wang, Gang, Tang, Zhengshan, Shan, Yali, Shen, Shiping, Ni, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215507/
https://www.ncbi.nlm.nih.gov/pubmed/37237853
http://dx.doi.org/10.3390/antiox12050987

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