One Billion hiPSC-Cardiomyocytes: Upscaling Engineered Cardiac Tissues to Create High Cell Density Therapies for Clinical Translation in Heart Regeneration

Despite the overwhelming use of cellularized therapeutics in cardiac regenerative engineering, approaches to biomanufacture engineered cardiac tissues (ECTs) at clinical scale remain limited. This study aims to evaluate the impact of critical biomanufacturing decisions—namely cell dose, hydrogel com...

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Detalles Bibliográficos
Autores principales: Dwyer, Kiera D., Kant, Rajeev J., Soepriatna, Arvin H., Roser, Stephanie M., Daley, Mark C., Sabe, Sharif A., Xu, Cynthia M., Choi, Bum-Rak, Sellke, Frank W., Coulombe, Kareen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215511/
https://www.ncbi.nlm.nih.gov/pubmed/37237658
http://dx.doi.org/10.3390/bioengineering10050587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215511/
https://www.ncbi.nlm.nih.gov/pubmed/37237658
http://dx.doi.org/10.3390/bioengineering10050587

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