Cargando…
Metabolic Functions of Biliverdin IXβ Reductase in Redox-Regulated Hematopoietic Cell Fate
Cytoprotective heme oxygenases derivatize heme to generate carbon monoxide, ferrous iron, and isomeric biliverdins, followed by rapid NAD(P)H-dependent biliverdin reduction to the antioxidant bilirubin. Recent studies have implicated biliverdin IXβ reductase (BLVRB) in a redox-regulated mechanism of...
Autores principales: | Bahou, Wadie F., Marchenko, Natalia, Nesbitt, Natasha M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215512/ https://www.ncbi.nlm.nih.gov/pubmed/37237924 http://dx.doi.org/10.3390/antiox12051058 |
Ejemplares similares
-
Genetic pathways regulating hematopoietic lineage speciation: Factorial latent variable model analysis of single cell transcriptome
por: Liu, Zhaoyan, et al.
Publicado: (2021) -
Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?
por: Jansen, Thomas, et al.
Publicado: (2012) -
Scalable production of biliverdin IXα by Escherichia coli
por: Chen, Dong, et al.
Publicado: (2012) -
Long-Term Effects of Biliverdin Reductase a Deficiency in Ugt1(−/−) Mice: Impact on Redox Status and Metabolism
por: Bortolussi, Giulia, et al.
Publicado: (2021) -
Biliverdin Reductase: More than a Namesake – The Reductase, Its Peptide Fragments, and Biliverdin Regulate Activity of the Three Classes of Protein Kinase C
por: Gibbs, Peter E. M., et al.
Publicado: (2012)