Cargando…

Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD

SIMPLE SUMMARY: Graft-versus-host disease is a potentially life-threatening complication after bone marrow transplantation from an unrelated donor. The multi-organ damage is triggered by the donor cells that attack the host tissue. Patients manifest signs and symptoms in the skin, liver, lungs and o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raman, Deepika, Chêne, Charlotte, Nicco, Carole, Jeljeli, Mohamed, Eu, Jie Qing, Clément, Marie-Véronique, Batteux, Frédéric, Pervaiz, Shazib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215844/ https://www.ncbi.nlm.nih.gov/pubmed/37237461 http://dx.doi.org/10.3390/biology12050647

Ejemplares similares

LPS(low)-Macrophages Alleviate the Outcome of Graft-Versus-Host Disease Without Aggravating Lymphoma Growth in Mice
por: Jeljeli, Mohamed, et al.
Publicado: (2021)

A Fenton-like cation can improve arsenic trioxide treatment of sclerodermatous chronic Graft-versus-Host Disease in mice
por: Chêne, Charlotte, et al.
Publicado: (2022)

Optimal combination of arsenic trioxide and copper ions to prevent autoimmunity in a murine HOCl-induced model of systemic sclerosis
por: Chêne, Charlotte, et al.
Publicado: (2023)

Implication of oxidative stress in the pathogenesis of systemic sclerosis via inflammation, autoimmunity and fibrosis
por: Doridot, Ludivine, et al.
Publicado: (2019)

Trained immunity modulates inflammation-induced fibrosis
por: Jeljeli, Mohamed, et al.
Publicado: (2019)

ROS Modulator Molecules with Therapeutic Potential in Cancers Treatments
por: Nicco, Carole, et al.
Publicado: (2017)

Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression
por: Raman, Deepika, et al.
Publicado: (2019)

A superoxide-driven redox state promotes geroconversion and resistance to senolysis in replication-stress associated senescence
por: Luo, Le, et al.
Publicado: (2023)

The redox-senescence axis and its therapeutic targeting
por: Ngoi, Natalie YL., et al.
Publicado: (2021)

Therapeutic Potential of Senolytics in Cardiovascular Disease
por: Dookun, Emily, et al.
Publicado: (2020)

TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3
por: Raman, Deepika, et al.
Publicado: (2021)

The Effects of Allicin, a Reactive Sulfur Species from Garlic, on a Selection of Mammalian Cell Lines
por: Gruhlke, Martin C. H., et al.
Publicado: (2016)

Paradoxes of senolytics
por: Blagosklonny, Mikhail V.
Publicado: (2018)

Senescence and Senolytics: State of the Art on Cellular Senescence, Senolytics, and Healthspan
por: Campisi, Judith
Publicado: (2020)

The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma
por: Kavian, Niloufar, et al.
Publicado: (2018)

Corrigendum: The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma
por: Kavian, Niloufar, et al.
Publicado: (2021)

Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc
por: Raman, Deepika, et al.
Publicado: (2020)

Interplay between Mitochondrial Metabolism and Cellular Redox State Dictates Cancer Cell Survival
por: Foo, Brittney Joy-Anne, et al.
Publicado: (2021)

A New Manganese Superoxide Dismutase Mimetic Improves Oxaliplatin-Induced Neuropathy and Global Tolerance in Mice
por: Prieux-Klotz, Caroline, et al.
Publicado: (2022)

Senolytic treatment reduces oxidative protein stress in an aging male murine model of post‐traumatic osteoarthritis
por: Chin, Alexander F., et al.
Publicado: (2023)

Increased cellular senescence in doxorubicin-induced murine ovarian injury: effect of senolytics
por: Gao, Yueyue, et al.
Publicado: (2023)

Senolytics improve muscle adaptation in old mice
por: Dungan, Cory M., et al.
Publicado: (2023)

Production of Superoxide Anions by Keratinocytes Initiates P. acnes-Induced Inflammation of the Skin
por: Grange, Philippe A., et al.
Publicado: (2009)

Amniotic Membrane Grafts for the Prevention of Esophageal Stricture after Circumferential Endoscopic Submucosal Dissection
por: Barret, Maximilien, et al.
Publicado: (2014)

Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
por: Doolittle, Madison L., et al.
Publicado: (2023)

Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance
por: Hirpara, Jayshree, et al.
Publicado: (2018)

Ultrasound-induced Cavitation enhances the efficacy of Chemotherapy in a 3D Model of Pancreatic Ductal Adenocarcinoma with its microenvironment
por: Leenhardt, R., et al.
Publicado: (2019)

Cell signaling and fate through the redox lens
por: Pervaiz, Shazib
Publicado: (2019)

Editorial: The proceedings of mitochondria apoptosis and cancer (MAC 2021) virtual symposium
por: Pervaiz, Shazib
Publicado: (2023)

Targeting anxiety and senescence with senolytics
por: Raffaele, Marco, et al.
Publicado: (2022)

Senolytics in the treatment of diabetic retinopathy
por: Hassan, Jannah Waled, et al.
Publicado: (2022)

Strategies for senolytic drug discovery
por: Power, Helen, et al.
Publicado: (2023)

Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human
por: Venkatachalam, Gireedhar, et al.
Publicado: (2009)

Neuroglial Senescence, α-Synucleinopathy, and the Therapeutic Potential of Senolytics in Parkinson’s Disease
por: Miller, Sean J., et al.
Publicado: (2022)

Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis
por: Günther, Sven, et al.
Publicado: (2018)

Senolytics and senostatics as adjuvant tumour therapy
por: Short, Susan, et al.
Publicado: (2019)

Senolytic drugs: from discovery to translation
por: Kirkland, J. L., et al.
Publicado: (2020)

Cardiac glycosides are broad-spectrum senolytics
por: Guerrero, Ana, et al.
Publicado: (2019)

SENOLYTIC DRUGS: DISCOVERY, TRANSLATION, AND APPLICATION
por: LeBrasseur, Nathan
Publicado: (2019)

Galactose‐modified duocarmycin prodrugs as senolytics
por: Guerrero, Ana, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t5soqrs6b45d3978k0964dq9b3