Mendelian Randomization Analysis Reveals Statins Potentially Increase Amyotrophic Lateral Sclerosis Risk Independent of Peripheral Cholesterol-Lowering Effects

Background: Observational studies suggest that statins may affect amyotrophic lateral sclerosis (ALS). However, they are limited by confounding and reverse causality biases. Therefore, we aimed to investigate the potential causal associations between statins and ALS using a mendelian randomization (...

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Detalles Bibliográficos
Autores principales: Wang, Wenjing, Zhang, Linjing, Xia, Kailin, Huang, Tao, Fan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216016/
https://www.ncbi.nlm.nih.gov/pubmed/37239030
http://dx.doi.org/10.3390/biomedicines11051359

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