Cargando…

Bidirectional TRP/L Type Ca(2+) Channel/RyR/BK(Ca) Molecular and Functional Signaloplex in Vascular Smooth Muscles

TRP channels are expressed both in vascular myocytes and endothelial cells, but knowledge of their operational mechanisms in vascular tissue is particularly limited. Here, we show for the first time the biphasic contractile reaction with relaxation followed by a contraction in response to TRPV4 agon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dryn, Dariia O., Melnyk, Mariia I., Melanaphy, Donal, Kizub, Igor V., Johnson, Christopher D., Zholos, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216084/ https://www.ncbi.nlm.nih.gov/pubmed/37238629 http://dx.doi.org/10.3390/biom13050759

Ejemplares similares

General anaesthesia-related complications of gut motility with a focus on cholinergic mechanisms, TRP channels and visceral pain
por: Zholos, Alexander V., et al.
Publicado: (2023)

Suppression of mI(CAT) in Mouse Small Intestinal Myocytes by General Anaesthetic Ketamine and its Recovery by TRPC4 Agonist (-)-englerin A
por: Melnyk, Mariia I., et al.
Publicado: (2020)

Age attenuates the T‐type Ca(V)3.2‐RyR axis in vascular smooth muscle
por: Fan, Gang, et al.
Publicado: (2020)

Both RyRs and TPCs are required for NAADP-induced intracellular Ca(2+) release
por: Gerasimenko, Julia V., et al.
Publicado: (2015)

Chronic fetal exposure to caffeine altered resistance vessel functions via RyRs-BK(Ca) down-regulation in rat offspring
por: Li, Na, et al.
Publicado: (2015)

Senolytics prevent caveolar Ca(V)3.2‐RyR axis malfunction in old vascular smooth muscle
por: Lin, Jie, et al.
Publicado: (2023)

Identification of ATP-Binding Regions in the RyR1 Ca(2+) Release Channel
por: Popova, Olga B., et al.
Publicado: (2012)

Sensory TRP channels contribute differentially to skin inflammation and persistent itch
por: Feng, Jing, et al.
Publicado: (2017)

RyR2 Modulates a Ca(2+)-Activated K(+) Current in Mouse Cardiac Myocytes
por: Mu, Yong-hui, et al.
Publicado: (2014)

Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1
por: Wei, Risheng, et al.
Publicado: (2016)

Acute RyR1 Ca(2+) leak enhances NADH-linked mitochondrial respiratory capacity
por: Zanou, Nadège, et al.
Publicado: (2021)

Ca(2+)-Dependent Phosphorylation of RyR2 Can Uncouple Channel Gating from Direct Cytosolic Ca(2+) Regulation
por: Carter, Simon, et al.
Publicado: (2011)

A Close Association of RyRs with Highly Dense Clusters of Ca(2+)-activated Cl(−) Channels Underlies the Activation of STICs by Ca(2+) Sparks in Mouse Airway Smooth Muscle
por: Bao, Rongfeng, et al.
Publicado: (2008)

Roles of IP(3)R and RyR Ca(2+) Channels in Endoplasmic Reticulum Stress and β-Cell Death
por: Luciani, Dan S., et al.
Publicado: (2009)

Acute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts
por: Zhang, Yanmin, et al.
Publicado: (2011)

Dantrolene-Induced Inhibition of Skeletal L-Type Ca(2+) Current Requires RyR1 Expression
por: Bannister, R. A.
Publicado: (2013)

Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca(2+) Release Patterns in Cardiomyocytes
por: Rajagopal, Vijay, et al.
Publicado: (2015)

Reconciling depressed Ca(2+) sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes
por: Ruiz-Hurtado, Gema, et al.
Publicado: (2015)

Ca(2+)-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains
por: Brohus, Malene, et al.
Publicado: (2019)

Exercise Training Stabilizes RyR2-Dependent Ca(2+) Release in Post-infarction Heart Failure
por: Danielsen, Tore Kristian, et al.
Publicado: (2021)

Expression of voltage-gated Ca(2+) channels, Insp(3)Rs, and RyRs in the immature mouse ovary
por: Bahena-Alvarez, Daniel, et al.
Publicado: (2022)

Regulation of Ca(2+) Sparks by Ca(2+) and Mg(2+) in Mammalian and Amphibian Muscle. An RyR Isoform-specific Role in Excitation–Contraction Coupling?
por: Zhou, Jingsong, et al.
Publicado: (2004)

Mitsugumin 53 regulates extracellular Ca(2+) entry and intracellular Ca(2+) release via Orai1 and RyR1 in skeletal muscle
por: Ahn, Mi Kyoung, et al.
Publicado: (2016)

Neuronal junctophilins recruit specific Ca(V) and RyR isoforms to ER-PM junctions and functionally alter Ca(V)2.1 and Ca(V)2.2
por: Perni, Stefano, et al.
Publicado: (2021)

Structure of RyR1 in native membranes
por: Chen, Wenbo, et al.
Publicado: (2020)

Single-Walled Carbon Nanotubes Inhibit TRPC4-Mediated Muscarinic Cation Current in Mouse Ileal Myocytes
por: Al Kury, Lina T., et al.
Publicado: (2021)

Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice
por: Wang, Qianqian, et al.
Publicado: (2019)

Luminal Ca(2+)–regulated Mg(2+) Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters
por: Laver, Derek R., et al.
Publicado: (2004)

Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca(2+) release in skeletal muscle
por: Sztretye, Monika, et al.
Publicado: (2011)

ß-Adrenergic Stimulation Increases RyR2 Activity via Intracellular Ca(2+) and Mg(2+) Regulation
por: Li, Jiao, et al.
Publicado: (2013)

Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes
por: Lifshitz, Lawrence M., et al.
Publicado: (2011)

Phosphorylation of RyR2 Ser‐2814 by CaMKII mediates β1‐adrenergic stress induced Ca(2+)‐leak from the sarcoplasmic reticulum
por: Baier, Maria J., et al.
Publicado: (2021)

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform
por: Venturi, Elisa, et al.
Publicado: (2018)

RYR2 Proteins Contribute to the Formation of Ca(2+) Sparks in Smooth Muscle
por: Ji, Guangju, et al.
Publicado: (2004)

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions
por: Greensmith, David J., et al.
Publicado: (2014)

Abnormal Ca(2+) homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modification
por: Zhang, Yanmin, et al.
Publicado: (2013)

Snapin, Positive Regulator of Stimulation- Induced Ca(2+) Release through RyR, Is Necessary for HIV-1 Replication in T Cells
por: Kinoshita, Shigemi M., et al.
Publicado: (2013)

Ryanodine receptor RyR1-mediated elevation of Ca(2+) concentration is required for the late stage of myogenic differentiation and fusion
por: Qiu, Kai, et al.
Publicado: (2022)

On the Adjacency Matrix of RyR2 Cluster Structures
por: Walker, Mark A., et al.
Publicado: (2015)

Review of RyR1 pathway and associated pathomechanisms
por: Witherspoon, Jessica W., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_m10r98pounim132s4nsjhod9el