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Targeting Hypoxia-Inducible Factor-1α for the Management of Hepatocellular Carcinoma
SIMPLE SUMMARY: Hypoxia, or low oxygen levels within tumor tissue, presents a significant challenge for the management of hepatocellular carcinoma (HCC). Hypoxic microenvironments can induce changes in gene expression and cellular metabolism that promote tumor growth, metastasis, and resistance to c...
Autores principales: | Huynh, Kenneth N., Rao, Sriram, Roth, Bradley, Bryan, Theodore, Fernando, Dayantha M., Dayyani, Farshid, Imagawa, David, Abi-Jaoudeh, Nadine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216171/ https://www.ncbi.nlm.nih.gov/pubmed/37345074 http://dx.doi.org/10.3390/cancers15102738 |
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