Cargando…

The Role of Thrombomodulin in Estrogen-Receptor-Positive Breast Cancer Progression, Metastasis, and Curcumin Sensitivity

Estrogen and estrogen receptors (ER) play a key role in breast cancer progression, which can be treated with endocrine therapy. Nevertheless, resistance to endocrine therapies is developed over time. The tumor expression of thrombomodulin (TM) is correlated with favorable prognosis in several types...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Chien-Yu, Wei, Po-Li, Prince, G. M. Shazzad Hossain, Batzorig, Uyanga, Lee, Cheng-Chin, Chang, Yu-Jia, Hung, Chin-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216190/ https://www.ncbi.nlm.nih.gov/pubmed/37239055 http://dx.doi.org/10.3390/biomedicines11051384

Ejemplares similares

Areca nut extract (ANE) inhibits the progression of hepatocellular carcinoma cells via activation of ROS production and activation of autophagy
por: Wei, Po-Li, et al.
Publicado: (2021)

Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53
por: Wang, Wei-Lin, et al.
Publicado: (2022)

Human α-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway
por: Wei, Po-Li, et al.
Publicado: (2022)

Glucose-Regulated Protein 94 Mediates the Proliferation and Metastasis through the Regulation of ETV1 and MAPK Pathway in Colorectal Cancer
por: Batzorig, Uyanga, et al.
Publicado: (2021)

Identification of Moesin (MSN) as a Potential Therapeutic Target for Colorectal Cancer via the β-Catenin-RUNX2 Axis
por: Huang, Chien-Yu, et al.
Publicado: (2023)

CWH43 Is a Novel Tumor Suppressor Gene with Negative Regulation of TTK in Colorectal Cancer
por: Lee, Cheng-Chin, et al.
Publicado: (2023)

IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis
por: Hung, Chin-Sheng, et al.
Publicado: (2017)

PCTAIRE Protein Kinase 1 (PCTK1) Suppresses Proliferation, Stemness, and Chemoresistance in Colorectal Cancer through the BMPR1B-Smad1/5/8 Signaling Pathway
por: Wei, Po-Li, et al.
Publicado: (2023)

Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers
por: Chiu, Jen-Hwey, et al.
Publicado: (2017)

Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer
por: Tsai, Kuei-Yen, et al.
Publicado: (2023)

Thrombomodulin regulates monocye differentiation via PKCδ and ERK1/2 pathway in vitro and in atherosclerotic artery
por: Tsai, Chien-Sung, et al.
Publicado: (2016)

Placental thrombomodulin expression in recurrent miscarriage
por: Stortoni, Piergiorgio, et al.
Publicado: (2010)

Chondrocyte Thrombomodulin Protects against Osteoarthritis
por: Kang, Lin, et al.
Publicado: (2023)

Association between arsenic exposure and soluble thrombomodulin: A cross sectional study in Bangladesh
por: Hasibuzzaman, M. M., et al.
Publicado: (2017)

A Thrombomodulin Gene Polymorphism (C1418T) Is Associated with Early Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery with a Conventional Cardiopulmonary Bypass during Hospitalization
por: Pai, Ching-Chou, et al.
Publicado: (2017)

Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells
por: Lee, Dahae, et al.
Publicado: (2021)

The role of thrombomodulin lectin-like domain in inflammation
por: Li, Yi-Heng, et al.
Publicado: (2012)

Thrombomodulin expression regulates tumorigenesis in bladder cancer
por: Wu, Chun-Te, et al.
Publicado: (2014)

Thrombomodulin Promotes Corneal Epithelial Wound Healing
por: Huang, Yi-Hsun, et al.
Publicado: (2015)

Recombinant thrombomodulin for secondary thrombotic thrombocytopenic purpura
por: Nakamura, Kensuke, et al.
Publicado: (2016)

Thrombomodulin Regulation of Mitogen-Activated Protein Kinases
por: Giri, Hemant, et al.
Publicado: (2019)

Thrombomodulin as a Physiological Modulator of Intravascular Injury
por: Watanabe-Kusunoki, Kanako, et al.
Publicado: (2020)

Thrombomodulin is upregulated in the kidneys of women with pre-eclampsia
por: van Aanhold, Cleo C. L., et al.
Publicado: (2021)

Thrombomodulin in patients with mild to moderate bleeding tendency
por: Mehic, Dino, et al.
Publicado: (2021)

Plasma thrombomodulin levels are associated with acute kidney injury in patients with acute heart failure
por: Lin, Shu-Min, et al.
Publicado: (2022)

Thrombomodulin Influences the Survival of Patients with Non-Metastatic Colorectal Cancer through Epithelial-To-Mesenchymal Transition (EMT)
por: Chang, Yu-Jia, et al.
Publicado: (2016)

Osteolytic effects of tumoral estrogen signaling in an estrogen receptor-positive breast cancer bone metastasis model
por: Cheng, Julia N., et al.
Publicado: (2021)

Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
por: Shankar, Sharmila, et al.
Publicado: (2008)

Pharmacological targeting of the thrombomodulin–protein C pathway mitigates radiation toxicity
por: Geiger, Hartmut, et al.
Publicado: (2012)

Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer
por: Chen, Chun-Chieh, et al.
Publicado: (2013)

Recombinant human thrombomodulin inhibits neutrophil extracellular trap formation in vitro
por: Shimomura, Yasuyo, et al.
Publicado: (2016)

Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival
por: Hanly, A M, et al.
Publicado: (2006)

Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis
por: Okamoto, Takayuki, et al.
Publicado: (2012)

Protective Role of Recombinant Human Thrombomodulin in Diabetes Mellitus
por: Okano, Yuko, et al.
Publicado: (2021)

Inhibition of TFF3 Enhances Sensitivity—and Overcomes Acquired Resistance—to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma
por: Poh, Han Ming, et al.
Publicado: (2019)

Dormancy Signatures and Metastasis in Estrogen Receptor Positive and Negative Breast Cancer
por: Kim, Ryung S., et al.
Publicado: (2012)

ESR1 alterations and metastasis in estrogen receptor positive breast cancer
por: Lei, Jonathan T., et al.
Publicado: (2019)

Effect of Estrogen on Heteronemin-Induced Anti-proliferative Effect in Breast Cancer Cells With Different Estrogen Receptor Status
por: Yang, Yu-Chen S. H., et al.
Publicado: (2021)

The inhibition of the estrogenic effects of pesticides and environmental chemicals by curcumin and isoflavonoids.
por: Verma, S P, et al.
Publicado: (1998)

Increased serum thrombomodulin level is associated with disease severity and mortality in pediatric sepsis
por: Lin, Jainn-Jim, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fql6g4g8v2sc85csm0rvpb1o8c