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Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center

SIMPLE SUMMARY: It is known that socioeconomically disadvantaged people more often develop esophageal cancer. Therefore, we assumed that those patients more often have advanced tumor stages and comorbidities at the time of surgery and, thus, are more likely to suffer from postoperative complications...

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Autores principales: Kemper, Marius, Zagorski, Jana, Wagner, Jonas, Graß, Julia-Kristin, Izbicki, Jakob R., Melling, Nathaniel, Wolter, Stefan, Reeh, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216220/
https://www.ncbi.nlm.nih.gov/pubmed/37345164
http://dx.doi.org/10.3390/cancers15102827
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author Kemper, Marius
Zagorski, Jana
Wagner, Jonas
Graß, Julia-Kristin
Izbicki, Jakob R.
Melling, Nathaniel
Wolter, Stefan
Reeh, Matthias
author_facet Kemper, Marius
Zagorski, Jana
Wagner, Jonas
Graß, Julia-Kristin
Izbicki, Jakob R.
Melling, Nathaniel
Wolter, Stefan
Reeh, Matthias
author_sort Kemper, Marius
collection PubMed
description SIMPLE SUMMARY: It is known that socioeconomically disadvantaged people more often develop esophageal cancer. Therefore, we assumed that those patients more often have advanced tumor stages and comorbidities at the time of surgery and, thus, are more likely to suffer from postoperative complications and poorer survival. To clarify this, we used the purchasing power of the respective postal codes to estimate the socioeconomic status (SES) of 310 patients who had undergone surgery for esophageal cancer in our institution. Fortunately, it turns out that SES was not associated with tumor stage or comorbidities at the time of surgery. Moreover, SES was neither related to postoperative complications nor overall survival. In conclusion, socioeconomic inequalities of patients treated at a high-volume center do not affect treatment results. ABSTRACT: In Germany, socioeconomically deprived citizens more often develop esophageal carcinoma, since typical risk factors follow the social gradient. Therefore, we hypothesized that socioeconomic deprivation might also be associated with advanced tumor stages and comorbidities at the time of surgery. As a consequence, socioeconomic deprivation may be related to postoperative complications and reduced overall survival. Therefore, 310 patients who had undergone esophagectomy for cancer in curative intent between 2012 and 2020 at the University Medical Center Hamburg-Eppendorf (UKE) were included in this study. Socioeconomic status (SES) was estimated using the purchasing power of patients’ postal codes as a surrogate parameter. No association was found between SES and tumor stage or comorbidities at the time of surgery. Moreover, SES was neither associated with postoperative complications nor overall survival. In conclusion, socioeconomic inequalities of patients treated at a high-volume center do not affect treatment outcomes.
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spelling pubmed-102162202023-05-27 Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center Kemper, Marius Zagorski, Jana Wagner, Jonas Graß, Julia-Kristin Izbicki, Jakob R. Melling, Nathaniel Wolter, Stefan Reeh, Matthias Cancers (Basel) Article SIMPLE SUMMARY: It is known that socioeconomically disadvantaged people more often develop esophageal cancer. Therefore, we assumed that those patients more often have advanced tumor stages and comorbidities at the time of surgery and, thus, are more likely to suffer from postoperative complications and poorer survival. To clarify this, we used the purchasing power of the respective postal codes to estimate the socioeconomic status (SES) of 310 patients who had undergone surgery for esophageal cancer in our institution. Fortunately, it turns out that SES was not associated with tumor stage or comorbidities at the time of surgery. Moreover, SES was neither related to postoperative complications nor overall survival. In conclusion, socioeconomic inequalities of patients treated at a high-volume center do not affect treatment results. ABSTRACT: In Germany, socioeconomically deprived citizens more often develop esophageal carcinoma, since typical risk factors follow the social gradient. Therefore, we hypothesized that socioeconomic deprivation might also be associated with advanced tumor stages and comorbidities at the time of surgery. As a consequence, socioeconomic deprivation may be related to postoperative complications and reduced overall survival. Therefore, 310 patients who had undergone esophagectomy for cancer in curative intent between 2012 and 2020 at the University Medical Center Hamburg-Eppendorf (UKE) were included in this study. Socioeconomic status (SES) was estimated using the purchasing power of patients’ postal codes as a surrogate parameter. No association was found between SES and tumor stage or comorbidities at the time of surgery. Moreover, SES was neither associated with postoperative complications nor overall survival. In conclusion, socioeconomic inequalities of patients treated at a high-volume center do not affect treatment outcomes. MDPI 2023-05-18 /pmc/articles/PMC10216220/ /pubmed/37345164 http://dx.doi.org/10.3390/cancers15102827 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kemper, Marius
Zagorski, Jana
Wagner, Jonas
Graß, Julia-Kristin
Izbicki, Jakob R.
Melling, Nathaniel
Wolter, Stefan
Reeh, Matthias
Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title_full Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title_fullStr Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title_full_unstemmed Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title_short Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
title_sort socioeconomic deprivation is not associated with outcomes after esophagectomy at a german high-volume center
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216220/
https://www.ncbi.nlm.nih.gov/pubmed/37345164
http://dx.doi.org/10.3390/cancers15102827
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