Single Fraction and Hypofractionated Radiation Cause Cochlear Damage, Hearing Loss, and Reduced Viability of Merlin-Deficient Schwann Cells

SIMPLE SUMMARY: Vestibular schwannomas are benign tumors of the eighth cranial nerve, caused by mutations in the NF2 gene encoding the tumor suppressor, merlin. A standard treatment for vestibular schwannoma is radiation therapy; however, radiation can cause sudden or progressive hearing loss in pat...

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Detalles Bibliográficos
Autores principales: Dinh, Christine T., Chen, Si, Nourbakhsh, Aida, Padgett, Kyle, Johnson, Perry, Goncalves, Stefania, Bracho, Olena, Bas, Esperanza, Bohorquez, Jorge, Monje, Paula V., Fernandez-Valle, Cristina, Elsayyad, Nagy, Liu, Xuezhong, Welford, Scott M., Telischi, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216287/
https://www.ncbi.nlm.nih.gov/pubmed/37345155
http://dx.doi.org/10.3390/cancers15102818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216287/
https://www.ncbi.nlm.nih.gov/pubmed/37345155
http://dx.doi.org/10.3390/cancers15102818

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