Cargando…

Comparative Evaluation of the Cytotoxicity of Doxorubicin in BT-20 Triple-Negative Breast Carcinoma Monolayer and Spheroid Cultures

Three-dimensional cell culture models are increasingly adopted as preferred pre-clinical drug testing platforms, as they circumvent limitations associated with traditional monolayer cell cultures. However, many of these models are not fully characterized. This study aimed to characterize a BT-20 tri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ncube, Keith N., Jurgens, Tamarin, Steenkamp, Vanessa, Cromarty, Allan D., van den Bout, Iman, Cordier, Werner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216410/ https://www.ncbi.nlm.nih.gov/pubmed/37239157 http://dx.doi.org/10.3390/biomedicines11051484

Ejemplares similares

Attenuation of oxidative stress in U937 cells by polyphenolic-rich bark fractions of Burkea africana and Syzygium cordatum
por: Cordier, Werner, et al.
Publicado: (2013)

Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
por: Ellero, Andrea Antonio, et al.
Publicado: (2021)

Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
por: van Vuuren, Rustelle Janse, et al.
Publicado: (2019)

Correction to: Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
por: van Vuuren, Rustelle Janse, et al.
Publicado: (2020)

A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions
por: Botes, Mandie, et al.
Publicado: (2018)

Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition
por: Burger, Trevor, et al.
Publicado: (2018)

Remote positioning system bt smv 20
por: Hourican, M
Publicado: (1997)

Antitumour activity and pharmacokinetics of niosome encapsulated adriamycin in monolayer, spheroid and xenograft.
por: Kerr, D. J., et al.
Publicado: (1988)

Baculovirus-assisted Reovirus Infection in Monolayer and Spheroid Cultures of Glioma cells
por: Dautzenberg, Iris J. C., et al.
Publicado: (2017)

Experimental virus evolution in cancer cell monolayers, spheroids, and tissue explants
por: Al-Zaher, Ahmed, et al.
Publicado: (2021)

In vitro determination of the anti-aging potential of four southern African medicinal plants
por: Ndlovu, Gugulethu, et al.
Publicado: (2013)

Spontaneous spheroid budding from monolayers: a potential contribution to ovarian cancer dissemination
por: Pease, Jillian C., et al.
Publicado: (2012)

Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model
por: Kunjithapatham, Rani, et al.
Publicado: (2014)

Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model
por: de la Mare, Jo-Anne, et al.
Publicado: (2017)

Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
por: Kaaijk, P., et al.
Publicado: (1996)

Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time
por: Baek, NamHuk, et al.
Publicado: (2016)

Endogenous Extracellular Matrix Regulates the Response of Osteosarcoma 3D Spheroids to Doxorubicin
por: Cortini, Margherita, et al.
Publicado: (2023)

Model of Ovarian Adenocarcinoma Spheroids for Assessing Photodynamic Cytotoxicity
por: Sokolova, E.A., et al.
Publicado: (2020)

Influence of reduced concentration of L-glutamine on growth and viability of cells in monolayer, in spheroids, and in experimental tumours.
por: Tannock, I. F., et al.
Publicado: (1986)

Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids
por: Nothisen, Marc, et al.
Publicado: (2018)

The response of gingiva monolayer, spheroid, and ex vivo tissue cultures to collagen membranes and bone substitute
por: Janjić, Klara, et al.
Publicado: (2020)

Demographic Performance of Helicoverpa zea Populations on Dual and Triple-Gene Bt Cotton
por: Rabelo, Marcelo M., et al.
Publicado: (2020)

Increased doxorubicin uptake and toxicity in multicellular tumour spheroids treated with DC electrical fields
por: Sauer, H, et al.
Publicado: (1999)

MINOS: Bt 599 intérieur - Bt 904
Publicado: (1992)

Light-Enhanced Cytotoxicity of Doxorubicin by Photoactivation
por: Greco, Giulia, et al.
Publicado: (2023)

The effect of adriamycin and 4'-deoxydoxorubicin on cell survival of human lung tumour cells grown in monolayer and as spheroids.
por: Kerr, D. J., et al.
Publicado: (1986)

Photocytotoxic efficacy of sulphonated species of aluminium phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumours.
por: Chan, W. S., et al.
Publicado: (1991)

Methylation Changes of Primary Tumors, Monolayer, and Spheroid Tissue Culture Environments in Malignant Melanoma and Breast Carcinoma
por: Şükrüoğlu Erdoğan, Özge, et al.
Publicado: (2019)

Ultrastructural Features of Gold Nanoparticles Interaction with HepG2 and HEK293 Cells in Monolayer and Spheroids
por: Chelobanov, Boris, et al.
Publicado: (2020)

Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers
por: Cray, Paul, et al.
Publicado: (2020)

Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity
por: Biswas, Dipsikha, et al.
Publicado: (2021)

Synthesis, Characterization, and In Vitro Cytotoxicity Evaluation of Doxorubicin-Loaded Magnetite Nanoparticles on Triple-Negative Breast Cancer Cell Lines
por: Markhulia, Jano, et al.
Publicado: (2023)

A Triple Combination of Metformin, Acetylsalicylic Acid, and Oseltamivir Phosphate Impacts Tumour Spheroid Viability and Upends Chemoresistance in Triple-Negative Breast Cancer
por: Sambi, Manpreet, et al.
Publicado: (2020)

Performance validation of the upgraded PSB Transfer Kicker BT2.KFA20
por: Coralejo Feliciano, Luis Miguel, et al.
Publicado: (2020)

Endothelial cell mitogen released from HT29 tumour cells grown in monolayer or multicellular spheroid culture.
por: Acker, H., et al.
Publicado: (1990)

Enhancement of thermal killing by polyamines V. The response of EMT6 multicellular tumour spheroids versus monolayer cells.
por: Ben-Hur, E., et al.
Publicado: (1983)

CD49f Is an Efficient Marker of Monolayer- and Spheroid Colony-Forming Cells of the Benign and Malignant Human Prostate
por: Yamamoto, Hidekazu, et al.
Publicado: (2012)

Proteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors
por: Martinez, Ramon, et al.
Publicado: (2022)

Utilizing two-dimensional monolayer and three-dimensional spheroids to enhance radiotherapeutic potential by combining gold nanoparticles and docetaxel
por: Bromma, Kyle, et al.
Publicado: (2023)

Response of EMT6 multicellular tumour spheroids to hyperthermia and cytotoxic drugs.
por: Morgan, J. E., et al.
Publicado: (1981)

Cannot write session to /tmp/vufind_sessions/sess_nfjpbr8g3n0cnm6rc8e6dk926k