Cargando…

Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients

SIMPLE SUMMARY: The research paper reported on a newly developed screening technique called Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) used for determining the most effective medication for breast cancer patients. The study found that the MTAM-HFA approach had a high level of accuracy in...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Shih-Hsin, Huang, Wan-Ting, Chew, Chee Ho, Chen, Amanda Lin, Chen, Shou-Tung, Chen, Jin-Hua, Hsieh, Yi-Chen, Chen, Chien-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216413/
https://www.ncbi.nlm.nih.gov/pubmed/37345100
http://dx.doi.org/10.3390/cancers15102764
_version_ 1785048292129767424
author Tu, Shih-Hsin
Huang, Wan-Ting
Chew, Chee Ho
Chen, Amanda Lin
Chen, Shou-Tung
Chen, Jin-Hua
Hsieh, Yi-Chen
Chen, Chien-Chung
author_facet Tu, Shih-Hsin
Huang, Wan-Ting
Chew, Chee Ho
Chen, Amanda Lin
Chen, Shou-Tung
Chen, Jin-Hua
Hsieh, Yi-Chen
Chen, Chien-Chung
author_sort Tu, Shih-Hsin
collection PubMed
description SIMPLE SUMMARY: The research paper reported on a newly developed screening technique called Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) used for determining the most effective medication for breast cancer patients. The study found that the MTAM-HFA approach had a high level of accuracy in predicting the patient’s response to the medication therapy, and there was a significant correlation between the screening outcome and the clinical outcome. The findings suggest that the MTAM-HFA technique has great potential for developing customized therapy for cancer care. With its ability to identify precise therapies for breast cancer patients, the MTAM-HFA screening method could transform cancer therapy, resulting in better outcomes for patients. The study provides valuable information for healthcare professionals and researchers working on breast cancer therapy research. ABSTRACT: Breast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the clinical results of a novel screening tool termed Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) in breast cancer patients in this clinical investigation. In all trial participants, the MTAM-HFA was utilized to identify active medicines for the treatment of breast cancer. The MTAM-HFA was shown to be extremely useful in predicting patient response to anticancer medication therapy in this study. Furthermore, the substantial association between the MTAM-HFA screening outcome and the clinical outcome of the respective patients emphasizes the promise of this unique screening technology in discovering effective anticancer medication combinations for the treatment of breast cancer. These findings indicate that the MTAM-HFA has clinical significance and might be a valuable tool in the development of tailored therapy for cancer care. This study provides helpful information for physicians and scientists working on breast cancer therapy research. The potential benefits of employing MTAM-HFA to find accurate therapies for breast cancer patients might lead to enhanced personalized medicine approaches to cancer care, resulting in better patient outcomes. Overall, the MTAM-HFA screening approach has the potential to revolutionize customized cancer therapy, providing hope to both patients and physicians.
format Online
Article
Text
id pubmed-10216413
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102164132023-05-27 Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients Tu, Shih-Hsin Huang, Wan-Ting Chew, Chee Ho Chen, Amanda Lin Chen, Shou-Tung Chen, Jin-Hua Hsieh, Yi-Chen Chen, Chien-Chung Cancers (Basel) Article SIMPLE SUMMARY: The research paper reported on a newly developed screening technique called Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) used for determining the most effective medication for breast cancer patients. The study found that the MTAM-HFA approach had a high level of accuracy in predicting the patient’s response to the medication therapy, and there was a significant correlation between the screening outcome and the clinical outcome. The findings suggest that the MTAM-HFA technique has great potential for developing customized therapy for cancer care. With its ability to identify precise therapies for breast cancer patients, the MTAM-HFA screening method could transform cancer therapy, resulting in better outcomes for patients. The study provides valuable information for healthcare professionals and researchers working on breast cancer therapy research. ABSTRACT: Breast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the clinical results of a novel screening tool termed Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) in breast cancer patients in this clinical investigation. In all trial participants, the MTAM-HFA was utilized to identify active medicines for the treatment of breast cancer. The MTAM-HFA was shown to be extremely useful in predicting patient response to anticancer medication therapy in this study. Furthermore, the substantial association between the MTAM-HFA screening outcome and the clinical outcome of the respective patients emphasizes the promise of this unique screening technology in discovering effective anticancer medication combinations for the treatment of breast cancer. These findings indicate that the MTAM-HFA has clinical significance and might be a valuable tool in the development of tailored therapy for cancer care. This study provides helpful information for physicians and scientists working on breast cancer therapy research. The potential benefits of employing MTAM-HFA to find accurate therapies for breast cancer patients might lead to enhanced personalized medicine approaches to cancer care, resulting in better patient outcomes. Overall, the MTAM-HFA screening approach has the potential to revolutionize customized cancer therapy, providing hope to both patients and physicians. MDPI 2023-05-15 /pmc/articles/PMC10216413/ /pubmed/37345100 http://dx.doi.org/10.3390/cancers15102764 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tu, Shih-Hsin
Huang, Wan-Ting
Chew, Chee Ho
Chen, Amanda Lin
Chen, Shou-Tung
Chen, Jin-Hua
Hsieh, Yi-Chen
Chen, Chien-Chung
Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title_full Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title_fullStr Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title_full_unstemmed Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title_short Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
title_sort unveiling the power of anticancer drug screening: a clinical case study comparing the effectiveness of hollow fiber assay microtube array membrane (mtam-hfa) in breast cancer patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216413/
https://www.ncbi.nlm.nih.gov/pubmed/37345100
http://dx.doi.org/10.3390/cancers15102764
work_keys_str_mv AT tushihhsin unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT huangwanting unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT chewcheeho unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT chenamandalin unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT chenshoutung unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT chenjinhua unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT hsiehyichen unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients
AT chenchienchung unveilingthepowerofanticancerdrugscreeningaclinicalcasestudycomparingtheeffectivenessofhollowfiberassaymicrotubearraymembranemtamhfainbreastcancerpatients