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Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study

Data on the use of device-aided therapies (DATs) in people with Parkinson’s disease (PwP) are scarce. Analyzing data from the Care4PD patient survey, we (1) evaluated application frequency and type of DAT in a larger, nationwide, cross-sectoral PwP sample in Germany; (2) analyzed the frequency of sy...

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Autores principales: Fründt, Odette, Hanff, Anne-Marie, Möhl, Annika, Mai, Tobias, Kirchner, Christiane, Amouzandeh, Ali, Buhmann, Carsten, Krüger, Rejko, Südmeyer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216485/
https://www.ncbi.nlm.nih.gov/pubmed/37239208
http://dx.doi.org/10.3390/brainsci13050736
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author Fründt, Odette
Hanff, Anne-Marie
Möhl, Annika
Mai, Tobias
Kirchner, Christiane
Amouzandeh, Ali
Buhmann, Carsten
Krüger, Rejko
Südmeyer, Martin
author_facet Fründt, Odette
Hanff, Anne-Marie
Möhl, Annika
Mai, Tobias
Kirchner, Christiane
Amouzandeh, Ali
Buhmann, Carsten
Krüger, Rejko
Südmeyer, Martin
author_sort Fründt, Odette
collection PubMed
description Data on the use of device-aided therapies (DATs) in people with Parkinson’s disease (PwP) are scarce. Analyzing data from the Care4PD patient survey, we (1) evaluated application frequency and type of DAT in a larger, nationwide, cross-sectoral PwP sample in Germany; (2) analyzed the frequency of symptoms indicative for advanced PD (aPD) and need for DAT amongst the remaining patients and (3) compared the most bothersome symptoms and need for professional long-term care (LTC) of patients with and without suspected aPD. Data from 1269 PwP were analyzed. In total, 153 PwP (12%) received DAT, mainly deep brain stimulation (DBS). Of the remaining 1116 PwP without DAT, >50% fulfilled at least one aPD criterion. Akinesia/rigidity and autonomic problems were most bothersome for PwP with and without suspected aPD, with more tremor in the non-aPD and more motor fluctuations and falls in the aPD group. To recapitulate, the German DAT application rate is rather low, although a large proportion of PwP fulfills aPD criteria indicating a need for intensified treatment strategies. Many reported bothersome symptoms could be overcome with DAT with benefits even for LTC patients. Thus, precise and early identification of aPD symptoms (and therapy-resistant tremor) should be implemented in future DAT preselection tools and educational trainings.
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spelling pubmed-102164852023-05-27 Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study Fründt, Odette Hanff, Anne-Marie Möhl, Annika Mai, Tobias Kirchner, Christiane Amouzandeh, Ali Buhmann, Carsten Krüger, Rejko Südmeyer, Martin Brain Sci Article Data on the use of device-aided therapies (DATs) in people with Parkinson’s disease (PwP) are scarce. Analyzing data from the Care4PD patient survey, we (1) evaluated application frequency and type of DAT in a larger, nationwide, cross-sectoral PwP sample in Germany; (2) analyzed the frequency of symptoms indicative for advanced PD (aPD) and need for DAT amongst the remaining patients and (3) compared the most bothersome symptoms and need for professional long-term care (LTC) of patients with and without suspected aPD. Data from 1269 PwP were analyzed. In total, 153 PwP (12%) received DAT, mainly deep brain stimulation (DBS). Of the remaining 1116 PwP without DAT, >50% fulfilled at least one aPD criterion. Akinesia/rigidity and autonomic problems were most bothersome for PwP with and without suspected aPD, with more tremor in the non-aPD and more motor fluctuations and falls in the aPD group. To recapitulate, the German DAT application rate is rather low, although a large proportion of PwP fulfills aPD criteria indicating a need for intensified treatment strategies. Many reported bothersome symptoms could be overcome with DAT with benefits even for LTC patients. Thus, precise and early identification of aPD symptoms (and therapy-resistant tremor) should be implemented in future DAT preselection tools and educational trainings. MDPI 2023-04-28 /pmc/articles/PMC10216485/ /pubmed/37239208 http://dx.doi.org/10.3390/brainsci13050736 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fründt, Odette
Hanff, Anne-Marie
Möhl, Annika
Mai, Tobias
Kirchner, Christiane
Amouzandeh, Ali
Buhmann, Carsten
Krüger, Rejko
Südmeyer, Martin
Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title_full Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title_fullStr Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title_full_unstemmed Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title_short Device-Aided Therapies in Parkinson’s Disease—Results from the German Care4PD Study
title_sort device-aided therapies in parkinson’s disease—results from the german care4pd study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216485/
https://www.ncbi.nlm.nih.gov/pubmed/37239208
http://dx.doi.org/10.3390/brainsci13050736
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