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Developing In Vitro Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis

The United States Food and Drug Administration Adverse Event Reporting System (FAERS) logged 27,140 rhabdomyolysis cases from 2004 to 31 March 2020. We used FAERS to identify 14 drugs frequently reported in 6583 rhabdomyolysis cases and to investigate whether mitochondrial toxicity is a common pathw...

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Detalles Bibliográficos
Autores principales: Bin Dayel, Faten F., Alfirevic, Ana, Chadwick, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216605/
https://www.ncbi.nlm.nih.gov/pubmed/37239154
http://dx.doi.org/10.3390/biomedicines11051485

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