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DCLK1 Drives EGFR-TKI-Acquired Resistance in Lung Adenocarcinoma by Remodeling the Epithelial–Mesenchymal Transition Status

Objective: Epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR-TKI) is a first-line treatment for lung adenocarcinoma with EGFR-sensitive mutations, but acquired resistance to EGFR-TKIs remains a problem in clinical practice. The development of epithelial–mesenchymal transition (EMT) is...

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Detalles Bibliográficos
Autores principales:	Yan, Rui, Huang, Xuying, Liu, Heshu, Xiao, Zeru, Liu, Jian, An, Guangyu, Ge, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216632/ https://www.ncbi.nlm.nih.gov/pubmed/37239162 http://dx.doi.org/10.3390/biomedicines11051490

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