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All-trans Retinoic Acid and Beta-Carotene Increase Sclerostin Production in C2C12 Myotubes

Sclerostin is a protein secreted by osteocytes whose encoding gene SOST is regulated by mechanical stimuli, cytokines, and all-trans retinoic acid (ATRA) and mediates antianabolic effects on bone formation as an inhibitor of the canonical Wnt/β-catenin pathway. Interestingly, skeletal muscle has rec...

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Detalles Bibliográficos
Autores principales:	Ewendt, Franz, Lehmann, Anne, Wodak, Maximilian F., Stangl, Gabriele I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216713/ https://www.ncbi.nlm.nih.gov/pubmed/37239103 http://dx.doi.org/10.3390/biomedicines11051432

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