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Targeting of microRNA-22 Suppresses Tumor Spread in a Mouse Model of Triple-Negative Breast Cancer
microRNA-22 (miR-22) is an oncogenic miRNA whose up-regulation promotes epithelial-mesenchymal transition (EMT), tumor invasion, and metastasis in hormone-responsive breast cancer. Here we show that miR-22 plays a key role in triple negative breast cancer (TNBC) by promoting EMT and aggressiveness i...
Autores principales: | Panella, Riccardo, Cotton, Cody A., Maymi, Valerie A., Best, Sachem, Berry, Kelsey E., Lee, Samuel, Batalini, Felipe, Vlachos, Ioannis S., Clohessy, John G., Kauppinen, Sakari, Paolo Pandolfi, Pier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216774/ https://www.ncbi.nlm.nih.gov/pubmed/37239141 http://dx.doi.org/10.3390/biomedicines11051470 |
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