DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation

Amyloidogenesis is one of the key pathophysiological changes in Alzheimer’s disease (AD). Accumulation of the toxic Aβ results from the catalytic processing of β-amyloid precursor protein (APP) associated β-amyloid converting enzyme 1 (BACE1) activity. It is reported that dead-box helicase 17 (DDX17...

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Detalles Bibliográficos
Autores principales: Liu, Yue, Zhou, Guifeng, Song, Li, Wen, Qixin, Xie, Shiqi, Chen, Long, Wang, Lu, Xie, Xiaoyong, Chen, Xue, Pu, Yalan, Chen, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216776/
https://www.ncbi.nlm.nih.gov/pubmed/37239217
http://dx.doi.org/10.3390/brainsci13050745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216776/
https://www.ncbi.nlm.nih.gov/pubmed/37239217
http://dx.doi.org/10.3390/brainsci13050745

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