Tissue-Specific Vulnerability to Apoptosis in Machado-Joseph Disease

Machado-Joseph disease (MJD) is a dominant neurodegenerative disease caused by an expanded CAG repeat in the ATXN3 gene encoding the ataxin-3 protein. Several cellular processes, including transcription and apoptosis, are disrupted in MJD. To gain further insights into the extent of dysregulation of...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana F., Raposo, Mafalda, Shaw, Emily D., Ashraf, Naila S., Medeiros, Filipa, Brilhante, Maria de Fátima, Perkins, Matthew, Vasconcelos, João, Kay, Teresa, Costa, Maria do Carmo, Lima, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216795/
https://www.ncbi.nlm.nih.gov/pubmed/37408238
http://dx.doi.org/10.3390/cells12101404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216795/
https://www.ncbi.nlm.nih.gov/pubmed/37408238
http://dx.doi.org/10.3390/cells12101404

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