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A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion
SIMPLE SUMMARY: The melanoma-conditioned microenvironment promotes immune escape and tumor progression, contributing to resistance to anti-melanoma immunotherapy in a large group of treated patients. While two-dimensional cultures lack tissue-context, animals poorly predict human immune responses. T...
Autores principales: | Michielon, Elisabetta, López González, Marta, Stolk, Dorian A., Stolwijk, Joeke G. C., Roffel, Sanne, Waaijman, Taco, Lougheed, Sinéad M., de Gruijl, Tanja D., Gibbs, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216824/ https://www.ncbi.nlm.nih.gov/pubmed/37345186 http://dx.doi.org/10.3390/cancers15102849 |
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