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Pulsed Radiofrequency Decreases pERK and Affects Intracellular Ca(2+) Influx, Cytosolic ATP Level, and Mitochondrial Membrane Potential in the Sensitized Dorsal Root Ganglion Neuron Induced by N-Methyl D-Aspartate
BACKGROUND: The molecular mechanism of pulsed radiofrequency (PRF) in chronic pain management is not fully understood. Chronic pain involves the activation of specific N-Methyl D-Aspartate receptors (NMDAR) to induce central sensitization. This study aims to determine the effect of PRF on central se...
Autores principales: | Laksono, Ristiawan Muji, Kalim, Handono, Rohman, Mohammad Saifur, Widodo, Nashi, Ahmad, Muhammad Ramli, Halim, Willy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216856/ https://www.ncbi.nlm.nih.gov/pubmed/37252110 http://dx.doi.org/10.2147/JPR.S409658 |
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