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Implication of the Transmembrane Domain in the Interleukin 10 Receptor Platform Oligomerisation

Interleukin 10 (IL-10) exerts anti-inflammatory and immune regulatory roles through its fixation to the IL-10 receptor (IL-10R). The two subunits (IL-10Rα and IL-10Rβ) organise themselves to form a hetero-tetramer to induce the activation of the transcription factor STAT3. We analysed the activation...

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Detalles Bibliográficos
Autores principales:	Kuntzel, Thomas, Spenlé, Caroline, Pham-Van, Lucas D., Birmpili, Dafni, Riou, Aurélien, Loeuillet, Aurore, Charmarke-Askar, Imane, Bagnard, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216903/ https://www.ncbi.nlm.nih.gov/pubmed/37408195 http://dx.doi.org/10.3390/cells12101361

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