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Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series

Inflammatory abdominal aortic aneurysms (iAAA) are a form of noninfectious aortitis in patients with abdominal aortic aneurysms (AAA). Ultrasound could help to detect iAAA early. This retrospective observational study assessed the potential of using ultrasound to detect iAAA in a case series of iAAA...

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Autores principales: Slijkhuis, Berend G. C., Liesker, David J., Konter, Sherilyn A. C., Possel-Nicolai, Annet, Bokkers, Reinoud P. H., Prakken, Niek H. J., Brouwer, Elisabeth, Slart, Riemer H. J. A., van Roon, Arie M., Saleem, Ben R., Mulder, Douwe J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216955/
https://www.ncbi.nlm.nih.gov/pubmed/37238153
http://dx.doi.org/10.3390/diagnostics13101669
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author Slijkhuis, Berend G. C.
Liesker, David J.
Konter, Sherilyn A. C.
Possel-Nicolai, Annet
Bokkers, Reinoud P. H.
Prakken, Niek H. J.
Brouwer, Elisabeth
Slart, Riemer H. J. A.
van Roon, Arie M.
Saleem, Ben R.
Mulder, Douwe J.
author_facet Slijkhuis, Berend G. C.
Liesker, David J.
Konter, Sherilyn A. C.
Possel-Nicolai, Annet
Bokkers, Reinoud P. H.
Prakken, Niek H. J.
Brouwer, Elisabeth
Slart, Riemer H. J. A.
van Roon, Arie M.
Saleem, Ben R.
Mulder, Douwe J.
author_sort Slijkhuis, Berend G. C.
collection PubMed
description Inflammatory abdominal aortic aneurysms (iAAA) are a form of noninfectious aortitis in patients with abdominal aortic aneurysms (AAA). Ultrasound could help to detect iAAA early. This retrospective observational study assessed the potential of using ultrasound to detect iAAA in a case series of iAAA patients, and the diagnostic value of ultrasound to detect iAAA in consecutive patients in a follow-up for AAA, referred to as a feasibility study. In both studies, diagnosis of iAAA was based on a cuff surrounding the aneurysm using CT (golden standard). The case series included 13 patients (age 64 (61; 72) years; 100% male). The feasibility study included 157 patients (age 75 (67; 80) years; 84% male). In the case series, all iAAA patients showed a cuff surrounding the aortic wall on ultrasound. In the feasibility study with AAA patients, ultrasound yielded no cuff in 147 (93.6%; CT negative in all cases), a typic cuff in 8 (5.1%; CT positive in all cases), and an inconclusive cuff in 2 (1.3%; CT negative in both cases) patients. Sensitivity and specificity were 100% and 98.7%, respectively. This study indicates that iAAA can be identified with ultrasound, and safely ruled out. In positive ultrasound cases, additional CT imaging might still be warranted.
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spelling pubmed-102169552023-05-27 Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series Slijkhuis, Berend G. C. Liesker, David J. Konter, Sherilyn A. C. Possel-Nicolai, Annet Bokkers, Reinoud P. H. Prakken, Niek H. J. Brouwer, Elisabeth Slart, Riemer H. J. A. van Roon, Arie M. Saleem, Ben R. Mulder, Douwe J. Diagnostics (Basel) Article Inflammatory abdominal aortic aneurysms (iAAA) are a form of noninfectious aortitis in patients with abdominal aortic aneurysms (AAA). Ultrasound could help to detect iAAA early. This retrospective observational study assessed the potential of using ultrasound to detect iAAA in a case series of iAAA patients, and the diagnostic value of ultrasound to detect iAAA in consecutive patients in a follow-up for AAA, referred to as a feasibility study. In both studies, diagnosis of iAAA was based on a cuff surrounding the aneurysm using CT (golden standard). The case series included 13 patients (age 64 (61; 72) years; 100% male). The feasibility study included 157 patients (age 75 (67; 80) years; 84% male). In the case series, all iAAA patients showed a cuff surrounding the aortic wall on ultrasound. In the feasibility study with AAA patients, ultrasound yielded no cuff in 147 (93.6%; CT negative in all cases), a typic cuff in 8 (5.1%; CT positive in all cases), and an inconclusive cuff in 2 (1.3%; CT negative in both cases) patients. Sensitivity and specificity were 100% and 98.7%, respectively. This study indicates that iAAA can be identified with ultrasound, and safely ruled out. In positive ultrasound cases, additional CT imaging might still be warranted. MDPI 2023-05-09 /pmc/articles/PMC10216955/ /pubmed/37238153 http://dx.doi.org/10.3390/diagnostics13101669 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Slijkhuis, Berend G. C.
Liesker, David J.
Konter, Sherilyn A. C.
Possel-Nicolai, Annet
Bokkers, Reinoud P. H.
Prakken, Niek H. J.
Brouwer, Elisabeth
Slart, Riemer H. J. A.
van Roon, Arie M.
Saleem, Ben R.
Mulder, Douwe J.
Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title_full Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title_fullStr Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title_full_unstemmed Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title_short Ultrasound for the Detection of Inflammatory Abdominal Aortic Aneurysms: A Case and Validation Series
title_sort ultrasound for the detection of inflammatory abdominal aortic aneurysms: a case and validation series
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216955/
https://www.ncbi.nlm.nih.gov/pubmed/37238153
http://dx.doi.org/10.3390/diagnostics13101669
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