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Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports

(1) Background: We aim to present our experience with resection of the inferior vena cava (IVC) without reconstruction in two patients diagnosed with renal tumors. (2) Case Report: The first case was diagnosed with right renal vein sarcoma and the second case was diagnosed with clear cell renal carc...

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Autores principales: Moldovan, Bogdan, Costache, Victor S., Modrigan, Irina, Farcas, Felix, Banu, Eugeniu, Untaru, Vlad, Stoica, Doly, Crisan, Madalina, Popianas, Andreea, Pisica, Radu-Mihai, Tohatan, Calin-Cristian, Adam, Iris-Iuliana, Vecerzan, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217086/
https://www.ncbi.nlm.nih.gov/pubmed/37238242
http://dx.doi.org/10.3390/diagnostics13101759
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author Moldovan, Bogdan
Costache, Victor S.
Modrigan, Irina
Farcas, Felix
Banu, Eugeniu
Untaru, Vlad
Stoica, Doly
Crisan, Madalina
Popianas, Andreea
Pisica, Radu-Mihai
Tohatan, Calin-Cristian
Adam, Iris-Iuliana
Vecerzan, Liliana
author_facet Moldovan, Bogdan
Costache, Victor S.
Modrigan, Irina
Farcas, Felix
Banu, Eugeniu
Untaru, Vlad
Stoica, Doly
Crisan, Madalina
Popianas, Andreea
Pisica, Radu-Mihai
Tohatan, Calin-Cristian
Adam, Iris-Iuliana
Vecerzan, Liliana
author_sort Moldovan, Bogdan
collection PubMed
description (1) Background: We aim to present our experience with resection of the inferior vena cava (IVC) without reconstruction in two patients diagnosed with renal tumors. (2) Case Report: The first case was diagnosed with right renal vein sarcoma and the second case was diagnosed with clear cell renal carcinoma; both presented signs of invasion and thrombosis of the IVC at infrarenal and cruoric levels, along with the development of collateral circulation with the help of the paravertebral plexus. In both patients, en bloc right nephrectomy was performed along with the resection of the thrombosed IVC without further reconstruction. In the case of the patient with right vein sarcoma, preservation of the left renal and caval intrahepatic vein was possible, whilst in the second case diagnosed with clear cell renal carcinoma, the associated left renal thrombosis also enforced the resection of the left renal vein. (3) Discussion: Postoperative evolution was favorable in both cases and did not exhibit major complications. Antibiotic therapy, analgesics, and anticoagulant medication were administered at therapeutic doses after surgery in both cases. The histopathological examination of the surgical specimen confirmed the diagnoses of renal vein sarcoma in the first case and clear cell renal carcinoma in the second case. Surgical treatment and adjuvant chemotherapy prolonged survival for two years for the first case and for two months, up until this moment, for the second case. The survival of clear cell renal carcinoma is currently at two months. (4) Conclusions: The resection of the inferior vena cava, without subsequent reconstruction in cases presenting diffused distal thrombosis, can represent an alternative to IVC reconstruction, which might lead to a major ulterior risk of thrombosis. In some cases, this can result in long-term survival.
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spelling pubmed-102170862023-05-27 Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports Moldovan, Bogdan Costache, Victor S. Modrigan, Irina Farcas, Felix Banu, Eugeniu Untaru, Vlad Stoica, Doly Crisan, Madalina Popianas, Andreea Pisica, Radu-Mihai Tohatan, Calin-Cristian Adam, Iris-Iuliana Vecerzan, Liliana Diagnostics (Basel) Case Report (1) Background: We aim to present our experience with resection of the inferior vena cava (IVC) without reconstruction in two patients diagnosed with renal tumors. (2) Case Report: The first case was diagnosed with right renal vein sarcoma and the second case was diagnosed with clear cell renal carcinoma; both presented signs of invasion and thrombosis of the IVC at infrarenal and cruoric levels, along with the development of collateral circulation with the help of the paravertebral plexus. In both patients, en bloc right nephrectomy was performed along with the resection of the thrombosed IVC without further reconstruction. In the case of the patient with right vein sarcoma, preservation of the left renal and caval intrahepatic vein was possible, whilst in the second case diagnosed with clear cell renal carcinoma, the associated left renal thrombosis also enforced the resection of the left renal vein. (3) Discussion: Postoperative evolution was favorable in both cases and did not exhibit major complications. Antibiotic therapy, analgesics, and anticoagulant medication were administered at therapeutic doses after surgery in both cases. The histopathological examination of the surgical specimen confirmed the diagnoses of renal vein sarcoma in the first case and clear cell renal carcinoma in the second case. Surgical treatment and adjuvant chemotherapy prolonged survival for two years for the first case and for two months, up until this moment, for the second case. The survival of clear cell renal carcinoma is currently at two months. (4) Conclusions: The resection of the inferior vena cava, without subsequent reconstruction in cases presenting diffused distal thrombosis, can represent an alternative to IVC reconstruction, which might lead to a major ulterior risk of thrombosis. In some cases, this can result in long-term survival. MDPI 2023-05-16 /pmc/articles/PMC10217086/ /pubmed/37238242 http://dx.doi.org/10.3390/diagnostics13101759 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Moldovan, Bogdan
Costache, Victor S.
Modrigan, Irina
Farcas, Felix
Banu, Eugeniu
Untaru, Vlad
Stoica, Doly
Crisan, Madalina
Popianas, Andreea
Pisica, Radu-Mihai
Tohatan, Calin-Cristian
Adam, Iris-Iuliana
Vecerzan, Liliana
Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title_full Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title_fullStr Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title_full_unstemmed Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title_short Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports
title_sort inferior vena cava (ivc) resections without reconstruction in renal tumors: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217086/
https://www.ncbi.nlm.nih.gov/pubmed/37238242
http://dx.doi.org/10.3390/diagnostics13101759
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