Cargando…

Overexpression of OLIG2 and MYT1L Transcription Factors Enhance the Differentiation Potential of Human Mesenchymal Stem Cells into Oligodendrocytes

Background: Demyelinating diseases represent a broad spectrum of disorders and are characterized by the loss of specialized glial cells (oligodendrocytes), which eventually leads to neuronal degeneration. Stem cell-based regenerative approaches provide therapeutic options to regenerate demyelination...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fahim, Ifrah, Ishaque, Aisha, Ramzan, Faiza, Shamsuddin, Shamsul Azlin Bin Ahmad, Ali, Anwar, Salim, Asmat, Khan, Irfan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217246/ https://www.ncbi.nlm.nih.gov/pubmed/37232730 http://dx.doi.org/10.3390/cimb45050261

Ejemplares similares

Co-regulation of Sox9 and TGFβ1 transcription factors in mesenchymal stem cells regenerated the intervertebral disc degeneration
por: Khalid, Shumaila, et al.
Publicado: (2023)

Decellularized Human Umbilical Tissue-Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells
por: Ramzan, Faiza, et al.
Publicado: (2022)

Identifying an oligodendrocyte enhancer that regulates Olig2 expression
por: Fan, Chuandong, et al.
Publicado: (2022)

Implications of Olig2 silencing in oligodendrocyte precursor cells
por: Fang, Li-Pao, et al.
Publicado: (2023)

The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents
por: Zhang, Kunkun, et al.
Publicado: (2022)

New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development
por: Paes de Faria, Joana, et al.
Publicado: (2014)

Effect of glycyrrhizic acid and 18β-glycyrrhetinic acid on the differentiation of human umbilical cord-mesenchymal stem cells into hepatocytes
por: Fatima, Abiha, et al.
Publicado: (2021)

Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation
por: Wedel, Miriam, et al.
Publicado: (2020)

Author Correction: The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents
por: Zhang, Kunkun, et al.
Publicado: (2022)

Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells
por: Ishaque, Aisha, et al.
Publicado: (2022)

A tool for examining the role of the zinc finger myelin transcription factor 1 (Myt1) in neural development: Myt1 knock-in mice
por: Hudson, Lynn D., et al.
Publicado: (2011)

Effects of the transcription factor Olig1 on the differentiation and remyelination of oligodendrocyte precursor cells after focal cerebral ischemia in rats
por: Zhao, Hong, et al.
Publicado: (2019)

Phosphorylation Regulates OLIG2 Cofactor Choice and the Motor Neuron-Oligodendrocyte Fate Switch
por: Li, Huiliang, et al.
Publicado: (2011)

OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation
por: Wei, Haichao, et al.
Publicado: (2021)

Myt1 overexpression mediates resistance to cell cycle and DNA damage checkpoint kinase inhibitors
por: Sokhi, Sargun, et al.
Publicado: (2023)

Promoting effect of small molecules in cardiomyogenic and neurogenic differentiation of rat bone marrow-derived mesenchymal stem cells
por: Khanabdali, Ramin, et al.
Publicado: (2015)

Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer
por: Küspert, Melanie, et al.
Publicado: (2011)

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation
por: Deng, Tao, et al.
Publicado: (2017)

Shh and Olig2 sequentially regulate oligodendrocyte differentiation from hiPSCs for the treatment of ischemic stroke
por: Xu, Jian, et al.
Publicado: (2022)

Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA
por: Xu, Jian, et al.
Publicado: (2022)

The Transcription Factor Myt3 Acts as a Pro-Survival Factor in β-cells
por: Tennant, Bryan R., et al.
Publicado: (2012)

Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia
por: CHENG, TONGFEI, et al.
Publicado: (2015)

MYT1 role in the microtia‐craniofacial microsomia spectrum
por: Luquetti, Daniela V., et al.
Publicado: (2020)

Molecular mechanisms of OLIG2 transcription factor in brain cancer
por: Tsigelny, Igor F., et al.
Publicado: (2016)

A Putative Transcription Factor MYT1 Is Required for Female Fertility in the Ascomycete Gibberella zeae
por: Lin, Yang, et al.
Publicado: (2011)

A Putative Transcription Factor MYT2 Regulates Perithecium Size in the Ascomycete Gibberella zeae
por: Lin, Yang, et al.
Publicado: (2012)

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome
por: Chakrabarti, Lina, et al.
Publicado: (2010)

One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2
por: Chanoumidou, Konstantina, et al.
Publicado: (2021)

Publisher Correction: Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA
por: Xu, Jian, et al.
Publicado: (2022)

Performance Evaluation of the MyT4 Technology for Determining ART Eligibility
por: Sitoe, Nádia, et al.
Publicado: (2016)

MYT3, A Myb-Like Transcription Factor, Affects Fungal Development and Pathogenicity of Fusarium graminearum
por: Kim, Yongsoo, et al.
Publicado: (2014)

A Myt1 family transcription factor defines neuronal fate by repressing non-neuronal genes
por: Lee, Joo, et al.
Publicado: (2019)

BMSCs promote the differentiation of NSCs into oligodendrocytes via mediating Id2 and Olig expression through BMP/Smad signaling pathway
por: Song, Peiwen, et al.
Publicado: (2018)

Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration
por: Khalid, Shumaila, et al.
Publicado: (2022)

Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells
por: Razzaq, Syeda Saima, et al.
Publicado: (2022)

Impact of Graphene Derivatives as Artificial Extracellular Matrices on Mesenchymal Stem Cells
por: Ikram, Rabia, et al.
Publicado: (2022)

MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis
por: Vasconcelos, Francisca F., et al.
Publicado: (2016)

Ultraconserved Elements in the Olig2 Promoter
por: Chen, Christina T. L., et al.
Publicado: (2008)

Impact of the Olig Family on Neurodevelopmental Disorders
por: Szu, Jenny, et al.
Publicado: (2021)

Promoting the Differentiation of Neural Progenitor Cells into Oligodendrocytes through the Induction of Olig2 Expression: A Transcriptomic Study Using RNA-seq Analysis
por: Pieczonka, Katarzyna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6j697gsn1uhi9iitp5rjpaah2m