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Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases

Cemento-osseous dysplasia (COD) is a form of benign fibro-osseous lesion of the jaw. We sought to evaluate the demographic and clinical presentations of COD by collecting and analyzing the demographic, clinical, radiographic, and pathologic data of COD diagnosed in our institution from 2017 to 2022....

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Autores principales: Decolibus, Katherine, Shahrabi-Farahani, Shokoufeh, Brar, Anmol, Rasner, Shane D., Aguirre, Sarah E., Owosho, Adepitan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217321/
https://www.ncbi.nlm.nih.gov/pubmed/37232789
http://dx.doi.org/10.3390/dj11050138
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author Decolibus, Katherine
Shahrabi-Farahani, Shokoufeh
Brar, Anmol
Rasner, Shane D.
Aguirre, Sarah E.
Owosho, Adepitan A.
author_facet Decolibus, Katherine
Shahrabi-Farahani, Shokoufeh
Brar, Anmol
Rasner, Shane D.
Aguirre, Sarah E.
Owosho, Adepitan A.
author_sort Decolibus, Katherine
collection PubMed
description Cemento-osseous dysplasia (COD) is a form of benign fibro-osseous lesion of the jaw. We sought to evaluate the demographic and clinical presentations of COD by collecting and analyzing the demographic, clinical, radiographic, and pathologic data of COD diagnosed in our institution from 2017 to 2022. Over this six-year period, the records of 191 patients with COD were reviewed. Most patients were African American and female. Eighty-five patients were diagnosed with florid COD (FLCOD), 63 with periapical COD (PCOD), and 43 with focal COD (FCOD). Twenty-eight (14.7%) patients presented symptoms. The most common symptom was pain. All the symptomatic cases of COD that were histopathologically diagnosed were osteomyelitis in the setting of COD. Symptomatic patients were older (mean of 61.3 years) than the asymptomatic patients (mean of 51.2 years). Due to the radiographic appearance of a radiolucency or a mixture of radiolucency and radiopacity, forty-five asymptomatic patients were biopsied. Most of the asymptomatic patients biopsied were patients with FCOD (n = 19, 54.3%), followed by PCOD (n = 16, 25.8%), and FLCOD (n = 10, 15.2%). FLCOD is the most common form of COD to present with symptoms. Due to the significant overlap in clinical and radiographic presentation with other entities, FCOD and PCOD remain a diagnostic challenge to dentists. In conclusion, we analyzed the demographic and clinical features of 191 new cases of COD, which reaffirms that cemento-osseous dysplasia is a condition that primarily affects middle-aged females of African descent and occurs more frequently in the mandible.
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spelling pubmed-102173212023-05-27 Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases Decolibus, Katherine Shahrabi-Farahani, Shokoufeh Brar, Anmol Rasner, Shane D. Aguirre, Sarah E. Owosho, Adepitan A. Dent J (Basel) Article Cemento-osseous dysplasia (COD) is a form of benign fibro-osseous lesion of the jaw. We sought to evaluate the demographic and clinical presentations of COD by collecting and analyzing the demographic, clinical, radiographic, and pathologic data of COD diagnosed in our institution from 2017 to 2022. Over this six-year period, the records of 191 patients with COD were reviewed. Most patients were African American and female. Eighty-five patients were diagnosed with florid COD (FLCOD), 63 with periapical COD (PCOD), and 43 with focal COD (FCOD). Twenty-eight (14.7%) patients presented symptoms. The most common symptom was pain. All the symptomatic cases of COD that were histopathologically diagnosed were osteomyelitis in the setting of COD. Symptomatic patients were older (mean of 61.3 years) than the asymptomatic patients (mean of 51.2 years). Due to the radiographic appearance of a radiolucency or a mixture of radiolucency and radiopacity, forty-five asymptomatic patients were biopsied. Most of the asymptomatic patients biopsied were patients with FCOD (n = 19, 54.3%), followed by PCOD (n = 16, 25.8%), and FLCOD (n = 10, 15.2%). FLCOD is the most common form of COD to present with symptoms. Due to the significant overlap in clinical and radiographic presentation with other entities, FCOD and PCOD remain a diagnostic challenge to dentists. In conclusion, we analyzed the demographic and clinical features of 191 new cases of COD, which reaffirms that cemento-osseous dysplasia is a condition that primarily affects middle-aged females of African descent and occurs more frequently in the mandible. MDPI 2023-05-19 /pmc/articles/PMC10217321/ /pubmed/37232789 http://dx.doi.org/10.3390/dj11050138 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Decolibus, Katherine
Shahrabi-Farahani, Shokoufeh
Brar, Anmol
Rasner, Shane D.
Aguirre, Sarah E.
Owosho, Adepitan A.
Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title_full Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title_fullStr Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title_full_unstemmed Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title_short Cemento-Osseous Dysplasia of the Jaw: Demographic and Clinical Analysis of 191 New Cases
title_sort cemento-osseous dysplasia of the jaw: demographic and clinical analysis of 191 new cases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217321/
https://www.ncbi.nlm.nih.gov/pubmed/37232789
http://dx.doi.org/10.3390/dj11050138
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