Molecular Evaluation of the Impact of Polymorphic Variants in Apoptotic (Bcl-2/Bax) and Proinflammatory Cytokine (TNF-α/IL-8) Genes on the Susceptibility and Progression of Myeloproliferative Neoplasms: A Case-Control Biomarker Study

The regulation of apoptosis (the programmed cell death) is dependent on the crucial involvement of BCL2 and BAX. The Bax-248G>A and Bcl-2-938 C>A polymorphic variations in the promoter sequences of the Bax and Bcl-2 gene have been recently associated with low Bax expression, progression to adv...

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Detalles Bibliográficos
Autores principales: Moawadh, Mamdoh S., Mir, Rashid, Tayeb, Faris J., Asim, Orooba, Ullah, Mohammad Fahad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217376/
https://www.ncbi.nlm.nih.gov/pubmed/37232720
http://dx.doi.org/10.3390/cimb45050251

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