Cargando…

The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study

Molar incisor hypomineralization (MIH) and deciduous molar hypomineralization (DMH) affect the first permanent molars and second primary molars, respectively, causing a greater dental treatment burden and worse oral health quality of life among affected children. We assessed the prevalence and risk...

Descripción completa

Detalles Bibliográficos
Autores principales: Berenstein Ajzman, Gisela, Dagon, Nurit, Iraqi, Rabea, Blumer, Sigalit, Fadela, Shada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217385/
https://www.ncbi.nlm.nih.gov/pubmed/37238451
http://dx.doi.org/10.3390/children10050903
_version_ 1785048524879036416
author Berenstein Ajzman, Gisela
Dagon, Nurit
Iraqi, Rabea
Blumer, Sigalit
Fadela, Shada
author_facet Berenstein Ajzman, Gisela
Dagon, Nurit
Iraqi, Rabea
Blumer, Sigalit
Fadela, Shada
author_sort Berenstein Ajzman, Gisela
collection PubMed
description Molar incisor hypomineralization (MIH) and deciduous molar hypomineralization (DMH) affect the first permanent molars and second primary molars, respectively, causing a greater dental treatment burden and worse oral health quality of life among affected children. We assessed the prevalence and risk factors of MIH and DMH among 1209 children aged 3–13 years who attended a university dental clinic in Israel in 2019–2020. Clinical examinations were conducted to assess the presence of DMH and MIH. Potential etiological factors of MIH and DMH, including demographics, the mother’s perinatal health, and the child’s medical history during the first three years of life, were retrieved using a questionnaire. To examine the associations between the demographic and clinical variables and the prevalence of MIH and DMH, continuous variables were tested using the Kruskal–Wallis test with Bonferroni corrections. Categorical variables were analyzed by chi-squared test. Multivariate logistic regression was conducted to evaluate which of the significant variables found in the univariate analysis could predict a diagnosis of both MIH and DMH. The prevalence of MIH and DMH was 10.3% and 6.0%, respectively. Age ≥ 5 years, taking medications during pregnancy and severe lesions were associated with a greater risk for a diagnosis of DMH + MIH. Multivariate logistic regression with adjustment for age showed that the severity of hypomineralization was positively and significantly associated with a diagnosis of MIH + DMH with an odds ratio of 4.18 (95% confidence interval 1.26–17.16), p = 0.03. MIH should be diagnosed and monitored in young children to prevent further deterioration. Moreover, a preventive and restorative program for MIH should be established.
format Online
Article
Text
id pubmed-10217385
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102173852023-05-27 The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study Berenstein Ajzman, Gisela Dagon, Nurit Iraqi, Rabea Blumer, Sigalit Fadela, Shada Children (Basel) Article Molar incisor hypomineralization (MIH) and deciduous molar hypomineralization (DMH) affect the first permanent molars and second primary molars, respectively, causing a greater dental treatment burden and worse oral health quality of life among affected children. We assessed the prevalence and risk factors of MIH and DMH among 1209 children aged 3–13 years who attended a university dental clinic in Israel in 2019–2020. Clinical examinations were conducted to assess the presence of DMH and MIH. Potential etiological factors of MIH and DMH, including demographics, the mother’s perinatal health, and the child’s medical history during the first three years of life, were retrieved using a questionnaire. To examine the associations between the demographic and clinical variables and the prevalence of MIH and DMH, continuous variables were tested using the Kruskal–Wallis test with Bonferroni corrections. Categorical variables were analyzed by chi-squared test. Multivariate logistic regression was conducted to evaluate which of the significant variables found in the univariate analysis could predict a diagnosis of both MIH and DMH. The prevalence of MIH and DMH was 10.3% and 6.0%, respectively. Age ≥ 5 years, taking medications during pregnancy and severe lesions were associated with a greater risk for a diagnosis of DMH + MIH. Multivariate logistic regression with adjustment for age showed that the severity of hypomineralization was positively and significantly associated with a diagnosis of MIH + DMH with an odds ratio of 4.18 (95% confidence interval 1.26–17.16), p = 0.03. MIH should be diagnosed and monitored in young children to prevent further deterioration. Moreover, a preventive and restorative program for MIH should be established. MDPI 2023-05-19 /pmc/articles/PMC10217385/ /pubmed/37238451 http://dx.doi.org/10.3390/children10050903 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Berenstein Ajzman, Gisela
Dagon, Nurit
Iraqi, Rabea
Blumer, Sigalit
Fadela, Shada
The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title_full The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title_fullStr The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title_full_unstemmed The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title_short The Prevalence of Developmental Enamel Defects in Israeli Children and Its Association with Perinatal Conditions: A Cross-Sectional Study
title_sort prevalence of developmental enamel defects in israeli children and its association with perinatal conditions: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217385/
https://www.ncbi.nlm.nih.gov/pubmed/37238451
http://dx.doi.org/10.3390/children10050903
work_keys_str_mv AT berensteinajzmangisela theprevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT dagonnurit theprevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT iraqirabea theprevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT blumersigalit theprevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT fadelashada theprevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT berensteinajzmangisela prevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT dagonnurit prevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT iraqirabea prevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT blumersigalit prevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy
AT fadelashada prevalenceofdevelopmentalenameldefectsinisraelichildrenanditsassociationwithperinatalconditionsacrosssectionalstudy