The Epigenetic Reader Protein SP140 Regulates Dendritic Cell Activation, Maturation and Tolerogenic Potential

SP140 is an epigenetic reader protein expressed predominantly in immune cells. GWAS studies have shown an association between SP140 single nucleotide polymorphisms (SNPs) and diverse autoimmune and inflammatory diseases, suggesting a possible pathogenic role for SP140 in immune-mediated diseases. We...

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Detalles Bibliográficos
Autores principales: Ghiboub, Mohammed, Bell, Matthew, Sinkeviciute, Dovile, Prinjha, Rab K., de Winther, Menno P. J., Harker, Nicola R., Tough, David F., de Jonge, Wouter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217447/
https://www.ncbi.nlm.nih.gov/pubmed/37232738
http://dx.doi.org/10.3390/cimb45050269

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