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Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair

Treatment options for hypoplastic borderline left ventricle (LV) are critically dependent on the development of the LV itself and include different types of univentricular palliation or biventricular repair performed at birth. Since hybrid palliation allows deferring major surgery to 4–6 months, in...

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Autores principales: Oreto, Lilia, Mandraffino, Giuseppe, Calaciura, Rita Emanuela, Poli, Daniela, Gitto, Placido, Saitta, Michele Benedetto, Bellanti, Ermanno, Carerj, Scipione, Zito, Concetta, Iorio, Fiore Salvatore, Guccione, Paolo, Agati, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217472/
https://www.ncbi.nlm.nih.gov/pubmed/37238407
http://dx.doi.org/10.3390/children10050859
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author Oreto, Lilia
Mandraffino, Giuseppe
Calaciura, Rita Emanuela
Poli, Daniela
Gitto, Placido
Saitta, Michele Benedetto
Bellanti, Ermanno
Carerj, Scipione
Zito, Concetta
Iorio, Fiore Salvatore
Guccione, Paolo
Agati, Salvatore
author_facet Oreto, Lilia
Mandraffino, Giuseppe
Calaciura, Rita Emanuela
Poli, Daniela
Gitto, Placido
Saitta, Michele Benedetto
Bellanti, Ermanno
Carerj, Scipione
Zito, Concetta
Iorio, Fiore Salvatore
Guccione, Paolo
Agati, Salvatore
author_sort Oreto, Lilia
collection PubMed
description Treatment options for hypoplastic borderline left ventricle (LV) are critically dependent on the development of the LV itself and include different types of univentricular palliation or biventricular repair performed at birth. Since hybrid palliation allows deferring major surgery to 4–6 months, in borderline cases, the decision can be postponed until the LV has expressed its growth potential. We aimed to evaluate anatomic modifications of borderline LV after hybrid palliation. We retrospectively reviewed data from 45 consecutive patients with hypoplastic LV who underwent hybrid palliation at birth between 2011 and 2015. Sixteen patients (mean weight 3.15 Kg) exhibited borderline LV and were considered for potential LV growth. After 5 months, five patients underwent univentricular palliation (Group 1), eight biventricular repairs (Group 2) and three died before surgery. Echocardiograms of Groups 1 and 2 were reviewed, comparing LV structures at birth and after 5 months. Although, at birth, all LV measurements were far below the normal limits, after 5 months, LV mass in Group 2 was almost normal, while in Group 1, no growth was evident. However, aortic root diameter and long axis ratio were significantly higher in Group 2 already at birth. Hybrid palliation can be positively considered as a “bridge-to-decision” for borderline LV. Echocardiography plays a key role in monitoring the growth of borderline LV.
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spelling pubmed-102174722023-05-27 Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair Oreto, Lilia Mandraffino, Giuseppe Calaciura, Rita Emanuela Poli, Daniela Gitto, Placido Saitta, Michele Benedetto Bellanti, Ermanno Carerj, Scipione Zito, Concetta Iorio, Fiore Salvatore Guccione, Paolo Agati, Salvatore Children (Basel) Article Treatment options for hypoplastic borderline left ventricle (LV) are critically dependent on the development of the LV itself and include different types of univentricular palliation or biventricular repair performed at birth. Since hybrid palliation allows deferring major surgery to 4–6 months, in borderline cases, the decision can be postponed until the LV has expressed its growth potential. We aimed to evaluate anatomic modifications of borderline LV after hybrid palliation. We retrospectively reviewed data from 45 consecutive patients with hypoplastic LV who underwent hybrid palliation at birth between 2011 and 2015. Sixteen patients (mean weight 3.15 Kg) exhibited borderline LV and were considered for potential LV growth. After 5 months, five patients underwent univentricular palliation (Group 1), eight biventricular repairs (Group 2) and three died before surgery. Echocardiograms of Groups 1 and 2 were reviewed, comparing LV structures at birth and after 5 months. Although, at birth, all LV measurements were far below the normal limits, after 5 months, LV mass in Group 2 was almost normal, while in Group 1, no growth was evident. However, aortic root diameter and long axis ratio were significantly higher in Group 2 already at birth. Hybrid palliation can be positively considered as a “bridge-to-decision” for borderline LV. Echocardiography plays a key role in monitoring the growth of borderline LV. MDPI 2023-05-11 /pmc/articles/PMC10217472/ /pubmed/37238407 http://dx.doi.org/10.3390/children10050859 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oreto, Lilia
Mandraffino, Giuseppe
Calaciura, Rita Emanuela
Poli, Daniela
Gitto, Placido
Saitta, Michele Benedetto
Bellanti, Ermanno
Carerj, Scipione
Zito, Concetta
Iorio, Fiore Salvatore
Guccione, Paolo
Agati, Salvatore
Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title_full Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title_fullStr Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title_full_unstemmed Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title_short Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair
title_sort hybrid palliation for hypoplastic borderline left ventricle: one more chance to biventricular repair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217472/
https://www.ncbi.nlm.nih.gov/pubmed/37238407
http://dx.doi.org/10.3390/children10050859
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