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An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol
Background: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development, which has recently been found to be associated with a higher prevalence of hypodontia. The aim of this international multicentre study is to determine the association between MIH and other developmental ano...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217515/ https://www.ncbi.nlm.nih.gov/pubmed/37232768 http://dx.doi.org/10.3390/dj11050117 |
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author | Rodd, Helen D. Nazzal, Hani Bonifacio, Clarissa Calil Ruth, Choe Wei Crombie, Felicity El Shahawy, Osama Folayan, Morenike Oluwatoyin Gambetta-Tessini, Karla Goyal, Ashima Hasmun, Noren Issa, Ahmad I. Jundi, Suhad Manton, David J. Narasimhan, Srinivasan Omar, Samah Parekh, Susan Popoola, Bamidele O Silva, Mihiri Taylor, Greig Naomi, Yang Qiyue |
author_facet | Rodd, Helen D. Nazzal, Hani Bonifacio, Clarissa Calil Ruth, Choe Wei Crombie, Felicity El Shahawy, Osama Folayan, Morenike Oluwatoyin Gambetta-Tessini, Karla Goyal, Ashima Hasmun, Noren Issa, Ahmad I. Jundi, Suhad Manton, David J. Narasimhan, Srinivasan Omar, Samah Parekh, Susan Popoola, Bamidele O Silva, Mihiri Taylor, Greig Naomi, Yang Qiyue |
author_sort | Rodd, Helen D. |
collection | PubMed |
description | Background: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development, which has recently been found to be associated with a higher prevalence of hypodontia. The aim of this international multicentre study is to determine the association between MIH and other developmental anomalies in different populations. Methods: Investigators were trained and calibrated for the assessment of MIH and dental anomalies and ethical approvals obtained in each participating country. The study aimed to recruit 584 children with MIH and 584 children without MIH. Patients aged 7–16 years who attend specialist clinics will be invited to participate. Children will undergo a clinical examination to determine the presence and severity of MIH, using an established index. The presence of any other anomalies, affecting tooth number, morphology, or position, will be documented. Panoramic radiographs will be assessed for dental anomalies and the presence of third permanent molars. Statistical analysis, using a chi squared test and regression analysis, will be performed to determine any differences in dental anomaly prevalence between the MIH and non-MIH group and to determine any association between dental anomalies and patient characteristics. Conclusion: This large-scale study has the potential to improve understanding about MIH with benefits for patient management. |
format | Online Article Text |
id | pubmed-10217515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102175152023-05-27 An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol Rodd, Helen D. Nazzal, Hani Bonifacio, Clarissa Calil Ruth, Choe Wei Crombie, Felicity El Shahawy, Osama Folayan, Morenike Oluwatoyin Gambetta-Tessini, Karla Goyal, Ashima Hasmun, Noren Issa, Ahmad I. Jundi, Suhad Manton, David J. Narasimhan, Srinivasan Omar, Samah Parekh, Susan Popoola, Bamidele O Silva, Mihiri Taylor, Greig Naomi, Yang Qiyue Dent J (Basel) Protocol Background: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development, which has recently been found to be associated with a higher prevalence of hypodontia. The aim of this international multicentre study is to determine the association between MIH and other developmental anomalies in different populations. Methods: Investigators were trained and calibrated for the assessment of MIH and dental anomalies and ethical approvals obtained in each participating country. The study aimed to recruit 584 children with MIH and 584 children without MIH. Patients aged 7–16 years who attend specialist clinics will be invited to participate. Children will undergo a clinical examination to determine the presence and severity of MIH, using an established index. The presence of any other anomalies, affecting tooth number, morphology, or position, will be documented. Panoramic radiographs will be assessed for dental anomalies and the presence of third permanent molars. Statistical analysis, using a chi squared test and regression analysis, will be performed to determine any differences in dental anomaly prevalence between the MIH and non-MIH group and to determine any association between dental anomalies and patient characteristics. Conclusion: This large-scale study has the potential to improve understanding about MIH with benefits for patient management. MDPI 2023-04-28 /pmc/articles/PMC10217515/ /pubmed/37232768 http://dx.doi.org/10.3390/dj11050117 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Protocol Rodd, Helen D. Nazzal, Hani Bonifacio, Clarissa Calil Ruth, Choe Wei Crombie, Felicity El Shahawy, Osama Folayan, Morenike Oluwatoyin Gambetta-Tessini, Karla Goyal, Ashima Hasmun, Noren Issa, Ahmad I. Jundi, Suhad Manton, David J. Narasimhan, Srinivasan Omar, Samah Parekh, Susan Popoola, Bamidele O Silva, Mihiri Taylor, Greig Naomi, Yang Qiyue An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title | An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title_full | An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title_fullStr | An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title_full_unstemmed | An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title_short | An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol |
title_sort | international investigation of molar incisor hypomineralisation (imih) and its association with dental anomalies: development of a protocol |
topic | Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217515/ https://www.ncbi.nlm.nih.gov/pubmed/37232768 http://dx.doi.org/10.3390/dj11050117 |
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